том 69 издание 16 страницы 5486-5489

Regioselective and Stereoselective Nucleophilic Ring Opening of Trifluoromethylated Cyclic Sulfates:  Asymmetric Synthesis of Both Enantiomers of syn-(3-Trifluoromethyl)isoserine

Тип публикацииJournal Article
Дата публикации2004-07-03
scimago Q2
wos Q1
БС1
SJR0.737
CiteScore6.1
Impact factor3.6
ISSN00223263, 15206904
Organic Chemistry
Краткое описание
A novel and efficient enantioselective synthesis of both enantiomers of syn-(3-trifluoromethyl)isoserine was achieved. Ring opening of trifluoromethylated cyclic sulfates 3, derived from enantiopure trifluoromethylated vicinal diols 2, with various nucleophiles occurred exclusively at C2 with inversion of chirality. Treatment of 4c and 4d, obtained by nucleophilic opening of 3a and 3b with PhCO2NH4, with (CF3SO2)2O followed by substitution with sodium azide, Jones oxidation, and hydrogenolysis furnished (2S,3S)-(N-benzoyl)-3-(trifluoromethyl)isoserine 9a and (2R,3R)-(N-benzoyl)-3-(trifluoromethyl)isoserine 9b, respectively.
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ГОСТ |
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Jiang Z. X., Qing F. Regioselective and Stereoselective Nucleophilic Ring Opening of Trifluoromethylated Cyclic Sulfates: Asymmetric Synthesis of Both Enantiomers of syn-(3-Trifluoromethyl)isoserine // Journal of Organic Chemistry. 2004. Vol. 69. No. 16. pp. 5486-5489.
ГОСТ со всеми авторами (до 50) Скопировать
Jiang Z. X., Qing F. Regioselective and Stereoselective Nucleophilic Ring Opening of Trifluoromethylated Cyclic Sulfates: Asymmetric Synthesis of Both Enantiomers of syn-(3-Trifluoromethyl)isoserine // Journal of Organic Chemistry. 2004. Vol. 69. No. 16. pp. 5486-5489.
RIS |
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TY - JOUR
DO - 10.1021/jo0497611
UR - https://doi.org/10.1021/jo0497611
TI - Regioselective and Stereoselective Nucleophilic Ring Opening of Trifluoromethylated Cyclic Sulfates: Asymmetric Synthesis of Both Enantiomers of syn-(3-Trifluoromethyl)isoserine
T2 - Journal of Organic Chemistry
AU - Jiang, Zhong Xing
AU - Qing, Fengling
PY - 2004
DA - 2004/07/03
PB - American Chemical Society (ACS)
SP - 5486-5489
IS - 16
VL - 69
PMID - 15287804
SN - 0022-3263
SN - 1520-6904
ER -
BibTex |
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@article{2004_Jiang,
author = {Zhong Xing Jiang and Fengling Qing},
title = {Regioselective and Stereoselective Nucleophilic Ring Opening of Trifluoromethylated Cyclic Sulfates: Asymmetric Synthesis of Both Enantiomers of syn-(3-Trifluoromethyl)isoserine},
journal = {Journal of Organic Chemistry},
year = {2004},
volume = {69},
publisher = {American Chemical Society (ACS)},
month = {jul},
url = {https://doi.org/10.1021/jo0497611},
number = {16},
pages = {5486--5489},
doi = {10.1021/jo0497611}
}
MLA
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Jiang, Zhong Xing, and Fengling Qing. “Regioselective and Stereoselective Nucleophilic Ring Opening of Trifluoromethylated Cyclic Sulfates: Asymmetric Synthesis of Both Enantiomers of syn-(3-Trifluoromethyl)isoserine.” Journal of Organic Chemistry, vol. 69, no. 16, Jul. 2004, pp. 5486-5489. https://doi.org/10.1021/jo0497611.