Concise Synthesis of Enantiopure α-Trifluoromethyl Alanines, Diamines, and Amino Alcohols via the Strecker-type Reaction
Тип публикации: Journal Article
Дата публикации: 2006-08-11
scimago Q2
wos Q1
БС1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
PubMed ID:
16930068
Organic Chemistry
Краткое описание
Diastereomerically pure alpha-trifluoromethyl alpha-amino nitriles obtained by Strecker-type reactions from chiral CF3 imines and iminium proved to be very attractive versatile intermediates for the synthesis of various alpha-trifluoromethyl amino compounds. From these synthons, both enantiomers of alpha-trifluoromethyl alanine, trifluoromethyl 1,2-diamines, and amino alcohols were conveniently obtained in enantiopure form in high yields in a few steps.
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Huguenot F., Brigaud T. Concise Synthesis of Enantiopure α-Trifluoromethyl Alanines, Diamines, and Amino Alcohols via the Strecker-type Reaction // Journal of Organic Chemistry. 2006. Vol. 71. No. 18. pp. 7075-7078.
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Huguenot F., Brigaud T. Concise Synthesis of Enantiopure α-Trifluoromethyl Alanines, Diamines, and Amino Alcohols via the Strecker-type Reaction // Journal of Organic Chemistry. 2006. Vol. 71. No. 18. pp. 7075-7078.
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TY - JOUR
DO - 10.1021/jo0607717
UR - https://doi.org/10.1021/jo0607717
TI - Concise Synthesis of Enantiopure α-Trifluoromethyl Alanines, Diamines, and Amino Alcohols via the Strecker-type Reaction
T2 - Journal of Organic Chemistry
AU - Huguenot, Florent
AU - Brigaud, T
PY - 2006
DA - 2006/08/11
PB - American Chemical Society (ACS)
SP - 7075-7078
IS - 18
VL - 71
PMID - 16930068
SN - 0022-3263
SN - 1520-6904
ER -
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BibTex (до 50 авторов)
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@article{2006_Huguenot,
author = {Florent Huguenot and T Brigaud},
title = {Concise Synthesis of Enantiopure α-Trifluoromethyl Alanines, Diamines, and Amino Alcohols via the Strecker-type Reaction},
journal = {Journal of Organic Chemistry},
year = {2006},
volume = {71},
publisher = {American Chemical Society (ACS)},
month = {aug},
url = {https://doi.org/10.1021/jo0607717},
number = {18},
pages = {7075--7078},
doi = {10.1021/jo0607717}
}
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MLA
Скопировать
Huguenot, Florent, and T Brigaud. “Concise Synthesis of Enantiopure α-Trifluoromethyl Alanines, Diamines, and Amino Alcohols via the Strecker-type Reaction.” Journal of Organic Chemistry, vol. 71, no. 18, Aug. 2006, pp. 7075-7078. https://doi.org/10.1021/jo0607717.