Asymmetric synthesis of spiro[isoxazolin-3,3'-oxindoles] via the catalytic 1,3-dipolar cycloaddition reaction of nitrile oxides.
Publication type: Journal Article
Publication date: 2014-08-04
scimago Q2
wos Q1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
PubMed ID:
25054839
Organic Chemistry
Abstract
A highly enantioselective 1,3-dipolar cycloaddition of nitrile oxides with 3-arylidene-oxindoles was realized by a chiral N,N'-dioxide-nickel(II) complex catalyst under mild reaction conditions. A series of spiro-isoxazoline-oxindole derivatives were obtained in moderate yields (up to 65%) with good regioselectivities (up to 99:1), excellent enantioselectivities (up to 99% ee), and exclusive diastereoselectivity as well.
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80
Total citations:
80
Citations from 2024:
6
(7.5%)
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MLA
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GOST
Copy
Lian X. et al. Asymmetric synthesis of spiro[isoxazolin-3,3'-oxindoles] via the catalytic 1,3-dipolar cycloaddition reaction of nitrile oxides. // Journal of Organic Chemistry. 2014. Vol. 79. No. 16. pp. 7703-7710.
GOST all authors (up to 50)
Copy
Lian X., Guo S., Wang G., Lin L., Liu X., Feng X. Asymmetric synthesis of spiro[isoxazolin-3,3'-oxindoles] via the catalytic 1,3-dipolar cycloaddition reaction of nitrile oxides. // Journal of Organic Chemistry. 2014. Vol. 79. No. 16. pp. 7703-7710.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/jo5012625
UR - https://doi.org/10.1021/jo5012625
TI - Asymmetric synthesis of spiro[isoxazolin-3,3'-oxindoles] via the catalytic 1,3-dipolar cycloaddition reaction of nitrile oxides.
T2 - Journal of Organic Chemistry
AU - Lian, Xiangjin
AU - Guo, Songsong
AU - Wang, Gang
AU - Lin, Li-Li
AU - Liu, Xiaohua
AU - Feng, Xiaoming
PY - 2014
DA - 2014/08/04
PB - American Chemical Society (ACS)
SP - 7703-7710
IS - 16
VL - 79
PMID - 25054839
SN - 0022-3263
SN - 1520-6904
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2014_Lian,
author = {Xiangjin Lian and Songsong Guo and Gang Wang and Li-Li Lin and Xiaohua Liu and Xiaoming Feng},
title = {Asymmetric synthesis of spiro[isoxazolin-3,3'-oxindoles] via the catalytic 1,3-dipolar cycloaddition reaction of nitrile oxides.},
journal = {Journal of Organic Chemistry},
year = {2014},
volume = {79},
publisher = {American Chemical Society (ACS)},
month = {aug},
url = {https://doi.org/10.1021/jo5012625},
number = {16},
pages = {7703--7710},
doi = {10.1021/jo5012625}
}
Cite this
MLA
Copy
Lian, Xiangjin, et al. “Asymmetric synthesis of spiro[isoxazolin-3,3'-oxindoles] via the catalytic 1,3-dipolar cycloaddition reaction of nitrile oxides..” Journal of Organic Chemistry, vol. 79, no. 16, Aug. 2014, pp. 7703-7710. https://doi.org/10.1021/jo5012625.