volume 74 issue 11 pages 4364-4367

Indium-Catalyzed Highly Efficient Three-Component Coupling of Aldehyde, Alkyne, and Amine via C−H Bond Activation

Publication typeJournal Article
Publication date2009-05-07
scimago Q2
wos Q1
SJR0.737
CiteScore6.1
Impact factor3.6
ISSN00223263, 15206904
PubMed ID:  19422248
Organic Chemistry
Abstract
In this paper, indium(III) chloride was found to be a highly effective catalyst for the three-component coupling reactions of aldehydes, alkynes, and amines (A(3)-coupling) via C-H activation. The reactions could be applied to both aromatic and aliphatic aldehydes and alkynes. Nearly quantitative yields of the desired products were obtained in most cases. No cocatalyst or activator is required, and water is the only byproduct in the reactions. Furthermore, a tentative mechanism of the InCl(3)-catalyzed one-pot, three-component coupling of aldehyde, alkyne, and amine is proposed.
Found 
Found 

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GOST |
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GOST Copy
Zhang Y. et al. Indium-Catalyzed Highly Efficient Three-Component Coupling of Aldehyde, Alkyne, and Amine via C−H Bond Activation // Journal of Organic Chemistry. 2009. Vol. 74. No. 11. pp. 4364-4367.
GOST all authors (up to 50) Copy
Zhang Y., Li P., Wang M., Wang L. Indium-Catalyzed Highly Efficient Three-Component Coupling of Aldehyde, Alkyne, and Amine via C−H Bond Activation // Journal of Organic Chemistry. 2009. Vol. 74. No. 11. pp. 4364-4367.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/jo900507v
UR - https://doi.org/10.1021/jo900507v
TI - Indium-Catalyzed Highly Efficient Three-Component Coupling of Aldehyde, Alkyne, and Amine via C−H Bond Activation
T2 - Journal of Organic Chemistry
AU - Zhang, Yicheng
AU - Li, Pinhua
AU - Wang, Min
AU - Wang, Lei
PY - 2009
DA - 2009/05/07
PB - American Chemical Society (ACS)
SP - 4364-4367
IS - 11
VL - 74
PMID - 19422248
SN - 0022-3263
SN - 1520-6904
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2009_Zhang,
author = {Yicheng Zhang and Pinhua Li and Min Wang and Lei Wang},
title = {Indium-Catalyzed Highly Efficient Three-Component Coupling of Aldehyde, Alkyne, and Amine via C−H Bond Activation},
journal = {Journal of Organic Chemistry},
year = {2009},
volume = {74},
publisher = {American Chemical Society (ACS)},
month = {may},
url = {https://doi.org/10.1021/jo900507v},
number = {11},
pages = {4364--4367},
doi = {10.1021/jo900507v}
}
MLA
Cite this
MLA Copy
Zhang, Yicheng, et al. “Indium-Catalyzed Highly Efficient Three-Component Coupling of Aldehyde, Alkyne, and Amine via C−H Bond Activation.” Journal of Organic Chemistry, vol. 74, no. 11, May. 2009, pp. 4364-4367. https://doi.org/10.1021/jo900507v.