Langmuir, volume 29, issue 48, pages 15032-15042

Ag2S Quantum Dots Conjugated Chitosan Nanospheres toward Light-Triggered Nitric Oxide Release and Near-Infrared Fluorescence Imaging

Publication typeJournal Article
Publication date2013-11-20
Journal: Langmuir
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor3.9
ISSN07437463, 15205827
Spectroscopy
Electrochemistry
Condensed Matter Physics
General Materials Science
Surfaces and Interfaces
Abstract
Nanoscaled light-triggered nitric oxide (NO) delivery vehicles with the ability of near-infrared (NIR) fluorescence imaging was presented, which consisted of chitosan (CS)-based S-nitrosothiols (SNO) and encapsulated silver sulfide quantum dots (Ag2S QDs). CS-SNO compounds that bore NO-storing functional groups were prepared via amino modification of chitosan. Water-soluble Ag2S QDs were synthesized and conjugated with the CS-SNO compounds with the aid of ethylenediaminetetraacetic acid (EDTA). The biocompatible Ag2S-CS-SNO nanospheres, with dimension of ∼117 nm, exhibited bright NIR fluorescence and satisfactory photostability under NIR irradiation. The Ag2S-CS-SNO nanospheres could release NO under irradiation of UV or visible light at physiological pH and temperature yet would hardly release NO if NIR irradiation was applied. Cell imaging was successfully performed, demonstrating that the Ag2S-CS-SNO nanospheres could emit readily observable NIR fluorescence and release NO in living cells. The NIR fluorescence imaging of the Ag2S-CS-SNO nanospheres did not interfere with the light-triggered NO release from them, which would provide new perspectives for the application of multifunctional nanostructured materials in diagnostics and imaging.

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GOST Copy
Tan L., Wan A., Li H. Ag2S Quantum Dots Conjugated Chitosan Nanospheres toward Light-Triggered Nitric Oxide Release and Near-Infrared Fluorescence Imaging // Langmuir. 2013. Vol. 29. No. 48. pp. 15032-15042.
GOST all authors (up to 50) Copy
Tan L., Wan A., Li H. Ag2S Quantum Dots Conjugated Chitosan Nanospheres toward Light-Triggered Nitric Oxide Release and Near-Infrared Fluorescence Imaging // Langmuir. 2013. Vol. 29. No. 48. pp. 15032-15042.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1021/la403028j
UR - https://doi.org/10.1021/la403028j
TI - Ag2S Quantum Dots Conjugated Chitosan Nanospheres toward Light-Triggered Nitric Oxide Release and Near-Infrared Fluorescence Imaging
T2 - Langmuir
AU - Wan, Ajun
AU - Tan, Lianjiang
AU - Li, Huili
PY - 2013
DA - 2013/11/20 00:00:00
PB - American Chemical Society (ACS)
SP - 15032-15042
IS - 48
VL - 29
SN - 0743-7463
SN - 1520-5827
ER -
BibTex |
Cite this
BibTex Copy
@article{2013_Tan,
author = {Ajun Wan and Lianjiang Tan and Huili Li},
title = {Ag2S Quantum Dots Conjugated Chitosan Nanospheres toward Light-Triggered Nitric Oxide Release and Near-Infrared Fluorescence Imaging},
journal = {Langmuir},
year = {2013},
volume = {29},
publisher = {American Chemical Society (ACS)},
month = {nov},
url = {https://doi.org/10.1021/la403028j},
number = {48},
pages = {15032--15042},
doi = {10.1021/la403028j}
}
MLA
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MLA Copy
Tan, Lianjiang, et al. “Ag2S Quantum Dots Conjugated Chitosan Nanospheres toward Light-Triggered Nitric Oxide Release and Near-Infrared Fluorescence Imaging.” Langmuir, vol. 29, no. 48, Nov. 2013, pp. 15032-15042. https://doi.org/10.1021/la403028j.
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