Unprecedented Oxidation of a Phenylglycinol-Derived 2-Pyridone: Enantioselective Synthesis of Polyhydroxypiperidines
Тип публикации: Journal Article
Дата публикации: 2001-09-20
SCImago Q1
Tоп 10% SCImago
WOS Q1
БС1
SJR: 1.007
CiteScore: 7.7
Impact factor: 4.7
ISSN: 15237060, 15237052
PubMed ID:
11594808
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Краткое описание
[reaction: see text]. The phenylglycinol-derived 2-pyridone 1 undergoes m-CPBA oxidation steroselectively leading to the chiral nonracemic unsaturated bicyclic hydroxylactam 2, from which the enantioselective synthesis of (3R,5R)-3,4,5-trihydroxypiperidine (16) and the formal synthesis of the azasugar epiisofagomine are described. The enantioselective synthesis of (S)-N-Boc-3-hydroxypiperidine and (3R,4S)-3,4-dihydroxypiperidine is also reported.
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ГОСТ
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Amat M. et al. Unprecedented Oxidation of a Phenylglycinol-Derived 2-Pyridone: Enantioselective Synthesis of Polyhydroxypiperidines // Organic Letters. 2001. Vol. 3. No. 21. pp. 3257-3260.
ГОСТ со всеми авторами (до 50)
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Amat M., Llor N., Huguet M., Molins E., Espinosa E., Bosch J. Unprecedented Oxidation of a Phenylglycinol-Derived 2-Pyridone: Enantioselective Synthesis of Polyhydroxypiperidines // Organic Letters. 2001. Vol. 3. No. 21. pp. 3257-3260.
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RIS
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TY - JOUR
DO - 10.1021/ol016418z
UR - https://doi.org/10.1021/ol016418z
TI - Unprecedented Oxidation of a Phenylglycinol-Derived 2-Pyridone: Enantioselective Synthesis of Polyhydroxypiperidines
T2 - Organic Letters
AU - Amat, Mercedes
AU - Llor, Núria
AU - Huguet, Marta
AU - Molins, E.
AU - Espinosa, Enrique
AU - Bosch, Joan
PY - 2001
DA - 2001/09/20
PB - American Chemical Society (ACS)
SP - 3257-3260
IS - 21
VL - 3
PMID - 11594808
SN - 1523-7060
SN - 1523-7052
ER -
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BibTex (до 50 авторов)
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@article{2001_Amat,
author = {Mercedes Amat and Núria Llor and Marta Huguet and E. Molins and Enrique Espinosa and Joan Bosch},
title = {Unprecedented Oxidation of a Phenylglycinol-Derived 2-Pyridone: Enantioselective Synthesis of Polyhydroxypiperidines},
journal = {Organic Letters},
year = {2001},
volume = {3},
publisher = {American Chemical Society (ACS)},
month = {sep},
url = {https://doi.org/10.1021/ol016418z},
number = {21},
pages = {3257--3260},
doi = {10.1021/ol016418z}
}
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MLA
Скопировать
Amat, Mercedes, et al. “Unprecedented Oxidation of a Phenylglycinol-Derived 2-Pyridone: Enantioselective Synthesis of Polyhydroxypiperidines.” Organic Letters, vol. 3, no. 21, Sep. 2001, pp. 3257-3260. https://doi.org/10.1021/ol016418z.
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