Organic Letters, volume 6, issue 17, pages 2901-2904
Synthesis of BILN 2061, an HCV NS3 Protease Inhibitor with Proven Antiviral Effect in Humans
Anne-Marie Faucher
1
,
Murray D. Bailey
1
,
Pierre L Beaulieu
1
,
Christian Brochu
1
,
Jean-Simon Duceppe
1
,
Jean-Marie Ferland
1
,
Elise Ghiro
1
,
Vida Gorys
1
,
Ted Halmos
1
,
Stephen H Kawai
1
,
Martin Poirier
1
,
Bruno Simoneau
1
,
CHARLES A. COLE
1
,
Montse Llinas-Brunet
1
1
Chemistry Department, Boehringer Ingelheim (Canada) Ltd., Research and Development, 2100 Cunard Street, Laval, (Québec) Canada H7S 2G5
|
Publication type: Journal Article
Publication date: 2004-07-21
Journal:
Organic Letters
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 5.2
ISSN: 15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
The synthesis of BILN 2061, an NS3 protease inhibitor with proven antiviral effect in humans, was accomplished in a convergent manner from four building blocks. The procedure described here was suitable for the preparation of multigram quantities of BILN 2061 for preclinical pharmacological evaluation.
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Citations by publishers
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5
10
15
20
25
30
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American Chemical Society (ACS)
28 publications, 28.57%
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1 publication, 1.02%
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1 publication, 1.02%
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Thieme
1 publication, 1.02%
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Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 1.02%
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5
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25
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- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Faucher A. et al. Synthesis of BILN 2061, an HCV NS3 Protease Inhibitor with Proven Antiviral Effect in Humans // Organic Letters. 2004. Vol. 6. No. 17. pp. 2901-2904.
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Faucher A., Bailey M. D., Beaulieu P. L., Brochu C., Duceppe J., Ferland J., Ghiro E., Gorys V., Halmos T., Kawai S. H., Poirier M., Simoneau B., COLE C., Llinas-Brunet M. Synthesis of BILN 2061, an HCV NS3 Protease Inhibitor with Proven Antiviral Effect in Humans // Organic Letters. 2004. Vol. 6. No. 17. pp. 2901-2904.
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TY - JOUR
DO - 10.1021/ol0489907
UR - https://doi.org/10.1021/ol0489907
TI - Synthesis of BILN 2061, an HCV NS3 Protease Inhibitor with Proven Antiviral Effect in Humans
T2 - Organic Letters
AU - Faucher, Anne-Marie
AU - Bailey, Murray D.
AU - Beaulieu, Pierre L
AU - Brochu, Christian
AU - Duceppe, Jean-Simon
AU - Ferland, Jean-Marie
AU - Ghiro, Elise
AU - Gorys, Vida
AU - Halmos, Ted
AU - Kawai, Stephen H
AU - Poirier, Martin
AU - Simoneau, Bruno
AU - Llinas-Brunet, Montse
AU - COLE, CHARLES A.
PY - 2004
DA - 2004/07/21 00:00:00
PB - American Chemical Society (ACS)
SP - 2901-2904
IS - 17
VL - 6
SN - 1523-7060
SN - 1523-7052
ER -
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@article{2004_Faucher,
author = {Anne-Marie Faucher and Murray D. Bailey and Pierre L Beaulieu and Christian Brochu and Jean-Simon Duceppe and Jean-Marie Ferland and Elise Ghiro and Vida Gorys and Ted Halmos and Stephen H Kawai and Martin Poirier and Bruno Simoneau and Montse Llinas-Brunet and CHARLES A. COLE},
title = {Synthesis of BILN 2061, an HCV NS3 Protease Inhibitor with Proven Antiviral Effect in Humans},
journal = {Organic Letters},
year = {2004},
volume = {6},
publisher = {American Chemical Society (ACS)},
month = {jul},
url = {https://doi.org/10.1021/ol0489907},
number = {17},
pages = {2901--2904},
doi = {10.1021/ol0489907}
}
Cite this
MLA
Copy
Faucher, Anne-Marie, et al. “Synthesis of BILN 2061, an HCV NS3 Protease Inhibitor with Proven Antiviral Effect in Humans.” Organic Letters, vol. 6, no. 17, Jul. 2004, pp. 2901-2904. https://doi.org/10.1021/ol0489907.