Organic Letters, volume 14, issue 1, pages 370-373

Vilsmeier-Type Reaction of Dimethylaminoalkenoyl Cyclopropanes: One-Pot Access to 2,3-Dihydrofuro [3,2-c]pyridin-4(5H)-ones

Publication typeJournal Article
Publication date2011-12-14
Journal: Organic Letters
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor5.2
ISSN15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A domino reaction of readily available 1-carbamoyl-1-dimethylaminoalkenoylcyclopropanes in the presence of triflic anhydride (Tf(2)O) in N,N-dimethylformamide (DMF) is described, which provides a facile one-pot access to 2,3-dihydrofuro[3,2-c]pyridin-4(5H)-ones via tandem formylation (Vilsmeier-type reaction), intramolecular cyclization, and ring-enlargement sequences.

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GOST |
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GOST Copy
Huang P. et al. Vilsmeier-Type Reaction of Dimethylaminoalkenoyl Cyclopropanes: One-Pot Access to 2,3-Dihydrofuro [3,2-c]pyridin-4(5H)-ones // Organic Letters. 2011. Vol. 14. No. 1. pp. 370-373.
GOST all authors (up to 50) Copy
Huang P., Zhang N., Zhang R., Dong D. Vilsmeier-Type Reaction of Dimethylaminoalkenoyl Cyclopropanes: One-Pot Access to 2,3-Dihydrofuro [3,2-c]pyridin-4(5H)-ones // Organic Letters. 2011. Vol. 14. No. 1. pp. 370-373.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1021/ol203124f
UR - https://doi.org/10.1021/ol203124f
TI - Vilsmeier-Type Reaction of Dimethylaminoalkenoyl Cyclopropanes: One-Pot Access to 2,3-Dihydrofuro [3,2-c]pyridin-4(5H)-ones
T2 - Organic Letters
AU - Dong, Dewen
AU - Huang, Peng
AU - Zhang, Ning
AU - Zhang, Rui
PY - 2011
DA - 2011/12/14 00:00:00
PB - American Chemical Society (ACS)
SP - 370-373
IS - 1
VL - 14
SN - 1523-7060
SN - 1523-7052
ER -
BibTex |
Cite this
BibTex Copy
@article{2011_Huang,
author = {Dewen Dong and Peng Huang and Ning Zhang and Rui Zhang},
title = {Vilsmeier-Type Reaction of Dimethylaminoalkenoyl Cyclopropanes: One-Pot Access to 2,3-Dihydrofuro [3,2-c]pyridin-4(5H)-ones},
journal = {Organic Letters},
year = {2011},
volume = {14},
publisher = {American Chemical Society (ACS)},
month = {dec},
url = {https://doi.org/10.1021/ol203124f},
number = {1},
pages = {370--373},
doi = {10.1021/ol203124f}
}
MLA
Cite this
MLA Copy
Huang, Peng, et al. “Vilsmeier-Type Reaction of Dimethylaminoalkenoyl Cyclopropanes: One-Pot Access to 2,3-Dihydrofuro [3,2-c]pyridin-4(5H)-ones.” Organic Letters, vol. 14, no. 1, Dec. 2011, pp. 370-373. https://doi.org/10.1021/ol203124f.
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