Organic Letters, volume 15, issue 16, pages 4174-4177
Development of a Practical, Asymmetric Synthesis of the Hepatitis C Virus Protease Inhibitor MK-5172
Jeffrey Kuethe
1
,
Yongli Zhong
1
,
Nobuyoshi Yasuda
1
,
Gregory L Beutner
1
,
Katherine Linn
1
,
Mary Kim
1
,
Benjamin Marcune
1
,
Spencer D. Dreher
1
,
Guy R Humphrey
1
,
Tao Pei
1
1
Process Chemistry, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065-0200, United States
|
Publication type: Journal Article
Publication date: 2013-08-06
Journal:
Organic Letters
scimago Q1
wos Q1
SJR: 1.245
CiteScore: 9.3
Impact factor: 4.9
ISSN: 15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
The development of a practical, asymmetric synthesis of the hepatitis C virus (HCV) protease inhibitor MK-5172 (1), an 18-membered macrocycle, is described.
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GOST
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Kuethe J. et al. Development of a Practical, Asymmetric Synthesis of the Hepatitis C Virus Protease Inhibitor MK-5172 // Organic Letters. 2013. Vol. 15. No. 16. pp. 4174-4177.
GOST all authors (up to 50)
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Kuethe J., Zhong Y., Yasuda N., Beutner G. L., Linn K., Kim M., Marcune B., Dreher S. D., Humphrey G. R., Pei T. Development of a Practical, Asymmetric Synthesis of the Hepatitis C Virus Protease Inhibitor MK-5172 // Organic Letters. 2013. Vol. 15. No. 16. pp. 4174-4177.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/ol401864t
UR - https://doi.org/10.1021/ol401864t
TI - Development of a Practical, Asymmetric Synthesis of the Hepatitis C Virus Protease Inhibitor MK-5172
T2 - Organic Letters
AU - Kuethe, Jeffrey
AU - Zhong, Yongli
AU - Yasuda, Nobuyoshi
AU - Beutner, Gregory L
AU - Linn, Katherine
AU - Kim, Mary
AU - Marcune, Benjamin
AU - Dreher, Spencer D.
AU - Humphrey, Guy R
AU - Pei, Tao
PY - 2013
DA - 2013/08/06
PB - American Chemical Society (ACS)
SP - 4174-4177
IS - 16
VL - 15
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2013_Kuethe,
author = {Jeffrey Kuethe and Yongli Zhong and Nobuyoshi Yasuda and Gregory L Beutner and Katherine Linn and Mary Kim and Benjamin Marcune and Spencer D. Dreher and Guy R Humphrey and Tao Pei},
title = {Development of a Practical, Asymmetric Synthesis of the Hepatitis C Virus Protease Inhibitor MK-5172},
journal = {Organic Letters},
year = {2013},
volume = {15},
publisher = {American Chemical Society (ACS)},
month = {aug},
url = {https://doi.org/10.1021/ol401864t},
number = {16},
pages = {4174--4177},
doi = {10.1021/ol401864t}
}
Cite this
MLA
Copy
Kuethe, Jeffrey, et al. “Development of a Practical, Asymmetric Synthesis of the Hepatitis C Virus Protease Inhibitor MK-5172.” Organic Letters, vol. 15, no. 16, Aug. 2013, pp. 4174-4177. https://doi.org/10.1021/ol401864t.