Springer Nature
Biotechnology Letters
,  том 23 ,  издание 19 ,  страницы 1603-1606

Asymmetric synthesis of (R)-2-chloro-1-(m-chlorophenyl)ethanol using acetone powder of Geotrichum candidum

Тип публикации: Journal Article
Дата публикации: 2001-01-01
Springer Nature
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БС2
SJR: 0.528
CiteScore: 5.4
Impact factor: 2.1
ISSN: 01415492, 15736776
General Medicine
Applied Microbiology and Biotechnology
Biotechnology
Bioengineering
Краткое описание
The asymmetric synthesis of (R)-2-chloro-1-(m-chlorophenyl)ethanol, a precursor for a key intermediate of an important class of drugs, was achieved by reduction of the corresponding ketone using an acetone powder of Geotrichum candidum with 98% ee and 94% yield based on the starting amount of ketone.
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ГОСТ |
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Hamada H. et al. Asymmetric synthesis of (R)-2-chloro-1-(m-chlorophenyl)ethanol using acetone powder of Geotrichum candidum // Biotechnology Letters. 2001. Vol. 23. No. 19. pp. 1603-1606.
ГОСТ со всеми авторами (до 50) Скопировать
Hamada H., Miura T., Kumobayashi H., MATSUDA T., Harada T., Kaoru N. Asymmetric synthesis of (R)-2-chloro-1-(m-chlorophenyl)ethanol using acetone powder of Geotrichum candidum // Biotechnology Letters. 2001. Vol. 23. No. 19. pp. 1603-1606.
RIS |
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TY - JOUR
DO - 10.1023/a:1011922823367
UR - https://doi.org/10.1023/a:1011922823367
TI - Asymmetric synthesis of (R)-2-chloro-1-(m-chlorophenyl)ethanol using acetone powder of Geotrichum candidum
T2 - Biotechnology Letters
AU - Hamada, Hiroki
AU - Miura, Takashi
AU - Kumobayashi, Hidenori
AU - MATSUDA, TOMOKO
AU - Harada, Tadao
AU - Kaoru, Nakamura
PY - 2001
DA - 2001/01/01
PB - Springer Nature
SP - 1603-1606
IS - 19
VL - 23
SN - 0141-5492
SN - 1573-6776
ER -
BibTex |
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@article{2001_Hamada,
author = {Hiroki Hamada and Takashi Miura and Hidenori Kumobayashi and TOMOKO MATSUDA and Tadao Harada and Nakamura Kaoru},
title = {Asymmetric synthesis of (R)-2-chloro-1-(m-chlorophenyl)ethanol using acetone powder of Geotrichum candidum},
journal = {Biotechnology Letters},
year = {2001},
volume = {23},
publisher = {Springer Nature},
month = {jan},
url = {https://doi.org/10.1023/a:1011922823367},
number = {19},
pages = {1603--1606},
doi = {10.1023/a:1011922823367}
}
MLA
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Hamada, Hiroki, et al. “Asymmetric synthesis of (R)-2-chloro-1-(m-chlorophenyl)ethanol using acetone powder of Geotrichum candidum.” Biotechnology Letters, vol. 23, no. 19, Jan. 2001, pp. 1603-1606. https://doi.org/10.1023/a:1011922823367.