Catecholates and mixed catecholate hydroxamates as artificial siderophores for mycobacteria
Steffen Wittmann
1
,
Lothar Heinisch
1
,
Ina Scherlitz Hofmann
1
,
Thomas Stoiber
1
,
Dorothe Ankel-Fuchs
2
,
Ute Möllmann
1
2
Grünenthal GmbH Aachen, Germany
|
Publication type: Journal Article
Publication date: 2004-01-01
scimago Q1
wos Q2
SJR: 0.785
CiteScore: 7.7
Impact factor: 3.6
ISSN: 09660844, 15728773
PubMed ID:
14977362
Metals and Alloys
General Biochemistry, Genetics and Molecular Biology
Biomaterials
General Agricultural and Biological Sciences
Abstract
Different mono-, bis- or triscatecholates and mixed mono- or biscatecholate hydroxamates were synthesized as potential siderophores for mycobacteria. Siderophore activity was tested by growth promotion assays using wild type strains and iron transport mutants of mycobacteria as well as Gram-negative bacteria. Some triscatecholates and biscatecholate hydroxamates were active in mutants of Mycobacterium smegmatis deficient in mycobactin and exochelin biosynthesis or exochelin permease, respectively, indicating an uptake route independent of the exochelin/mycobactin pathway. Structure activity relationships were studied. Ampicillin conjugates of some of these compounds were inactive against mycobacteria but active against Gram-negative bacteria.
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12
Total citations:
12
Citations from 2024:
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(8.33%)
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GOST
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Wittmann S. et al. Catecholates and mixed catecholate hydroxamates as artificial siderophores for mycobacteria // BioMetals. 2004. Vol. 17. No. 1. pp. 53-64.
GOST all authors (up to 50)
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Wittmann S., Heinisch L., Scherlitz Hofmann I., Stoiber T., Ankel-Fuchs D., Möllmann U. Catecholates and mixed catecholate hydroxamates as artificial siderophores for mycobacteria // BioMetals. 2004. Vol. 17. No. 1. pp. 53-64.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1023/a:1024409517626
UR - https://doi.org/10.1023/a:1024409517626
TI - Catecholates and mixed catecholate hydroxamates as artificial siderophores for mycobacteria
T2 - BioMetals
AU - Wittmann, Steffen
AU - Heinisch, Lothar
AU - Scherlitz Hofmann, Ina
AU - Stoiber, Thomas
AU - Ankel-Fuchs, Dorothe
AU - Möllmann, Ute
PY - 2004
DA - 2004/01/01
PB - Springer Nature
SP - 53-64
IS - 1
VL - 17
PMID - 14977362
SN - 0966-0844
SN - 1572-8773
ER -
Cite this
BibTex (up to 50 authors)
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@article{2004_Wittmann,
author = {Steffen Wittmann and Lothar Heinisch and Ina Scherlitz Hofmann and Thomas Stoiber and Dorothe Ankel-Fuchs and Ute Möllmann},
title = {Catecholates and mixed catecholate hydroxamates as artificial siderophores for mycobacteria},
journal = {BioMetals},
year = {2004},
volume = {17},
publisher = {Springer Nature},
month = {jan},
url = {https://doi.org/10.1023/a:1024409517626},
number = {1},
pages = {53--64},
doi = {10.1023/a:1024409517626}
}
Cite this
MLA
Copy
Wittmann, Steffen, et al. “Catecholates and mixed catecholate hydroxamates as artificial siderophores for mycobacteria.” BioMetals, vol. 17, no. 1, Jan. 2004, pp. 53-64. https://doi.org/10.1023/a:1024409517626.