Changing Views of the Role of Langerhans Cells
Publication type: Journal Article
Publication date: 2012-03-01
scimago Q1
wos Q1
SJR: 1.659
CiteScore: 8.7
Impact factor: 5.7
ISSN: 0022202X, 15231747
PubMed ID:
22217741
Biochemistry
Molecular Biology
Cell Biology
Dermatology
Abstract
Langerhans cells (LCs) have long been considered to be the major sensitizing cells in the skin by initiating productive immunity in naive resting T cells. This picture has changed over the past decade. We now know (i) that the skin also harbors other types of dendritic antigen-presenting cells and (ii) that the genetically driven removal of the LC population results in increased T-cell immunity against haptens and infectious agents. It is not clear at present whether the situation in genetically modified mice is in any way indicative of the actual in vivo function of LCs. Exciting and challenging years lie ahead of the LC research community.
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Total citations:
120
Citations from 2024:
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(3.33%)
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MLA
Cite this
GOST
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Romani N., Brunner P. M., Stingl G. Changing Views of the Role of Langerhans Cells // Journal of Investigative Dermatology. 2012. Vol. 132. No. 3. pp. 872-881.
GOST all authors (up to 50)
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Romani N., Brunner P. M., Stingl G. Changing Views of the Role of Langerhans Cells // Journal of Investigative Dermatology. 2012. Vol. 132. No. 3. pp. 872-881.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1038/jid.2011.437
UR - https://doi.org/10.1038/jid.2011.437
TI - Changing Views of the Role of Langerhans Cells
T2 - Journal of Investigative Dermatology
AU - Romani, Nikolaus
AU - Brunner, Patrick M.
AU - Stingl, G.
PY - 2012
DA - 2012/03/01
PB - Elsevier
SP - 872-881
IS - 3
VL - 132
PMID - 22217741
SN - 0022-202X
SN - 1523-1747
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2012_Romani,
author = {Nikolaus Romani and Patrick M. Brunner and G. Stingl},
title = {Changing Views of the Role of Langerhans Cells},
journal = {Journal of Investigative Dermatology},
year = {2012},
volume = {132},
publisher = {Elsevier},
month = {mar},
url = {https://doi.org/10.1038/jid.2011.437},
number = {3},
pages = {872--881},
doi = {10.1038/jid.2011.437}
}
Cite this
MLA
Copy
Romani, Nikolaus, et al. “Changing Views of the Role of Langerhans Cells.” Journal of Investigative Dermatology, vol. 132, no. 3, Mar. 2012, pp. 872-881. https://doi.org/10.1038/jid.2011.437.