Nature Cell Biology, volume 26, issue 10, pages 1625-1628
Criteria for the standardization of stem-cell-based embryo models
Alfonso Arias
1
,
Nicolas Rivron
2
,
Naomi Moris
3
,
Patrick Tam
4
,
C. Alev
5
,
Jianping Fu
6, 7, 8
,
Anna-Katerina Hadjantonakis
9
,
Jacob H. Hanna
10
,
Gabriella Minchiotti
11
,
Olivier Pourquié
12
,
Guojun Sheng
13
,
L. Solnica-Krezel
14
,
Jesse V. Veenvliet
15, 16, 17
,
Aryeh Warmflash
18, 19
8
11
Institute of Genetics and Biophysics, A. Buzzati-Traverso, CNR, Naples, Italy
|
17
Center for Systems Biology Dresden, Dresden, Germany
|
Publication type: Journal Article
Publication date: 2024-09-02
Journal:
Nature Cell Biology
scimago Q1
SJR: 8.913
CiteScore: 28.4
Impact factor: 17.3
ISSN: 14657392, 14764679
Abstract
Pluripotent stem cells are being used to generate models of early embryogenesis that are promising for discovery and translational research. To be useful, these models require critical consideration of their level of efficiency and fidelity to natural embryos. Here we propose criteria with which to raise the standards of stem-cell-based embryo models of human embryogenesis.
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