Nature Cell Biology, volume 26, issue 10, pages 1625-1628

Criteria for the standardization of stem-cell-based embryo models

Alfonso Arias 1
Nicolas Rivron 2
Naomi Moris 3
Patrick Tam 4
C. Alev 5
Jianping Fu 6, 7, 8
Anna-Katerina Hadjantonakis 9
Jacob H. Hanna 10
Gabriella Minchiotti 11
Olivier Pourquié 12
Guojun Sheng 13
Jesse V. Veenvliet 15, 16, 17
Aryeh Warmflash 18, 19
Show full list: 14 authors
11
 
Institute of Genetics and Biophysics, A. Buzzati-Traverso, CNR, Naples, Italy
17
 
Center for Systems Biology Dresden, Dresden, Germany
Publication typeJournal Article
Publication date2024-09-02
scimago Q1
SJR8.913
CiteScore28.4
Impact factor17.3
ISSN14657392, 14764679
Abstract
Pluripotent stem cells are being used to generate models of early embryogenesis that are promising for discovery and translational research. To be useful, these models require critical consideration of their level of efficiency and fidelity to natural embryos. Here we propose criteria with which to raise the standards of stem-cell-based embryo models of human embryogenesis.
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