Nature Physics, volume 14, issue 10, pages 1062-1066

Experimental evidence for ultrafast intermolecular relaxation processes in hydrated biomolecules

Ren Xueguang ^{1, 2}

Wang Enliang ¹

Skitnevskaya A D ³

Trofimov A.B. ^{3, 4}

Gokhberg Kirill ⁵

Dorn Alexander ¹

Hide authors affiliations Show authors affiliations: 5 affiliations

Max-Planck-Institut für Kernphysik, Heidelberg, Germany |

School of science, Xi’an Jiaotong University, Xi’an, China |

Laboratory of Quantum Chemistry, Irkutsk State University, Irkutsk, Russia |

⁴

Favorsky’s Institute of Chemistry, SB RAS, Irkutsk, Russia |

⁵

Theoretische Chemie, Physikalisch-Chemisches Institut, Universität Heidelberg, Heidelberg, Germany |

Publication type: Journal Article

Publication date: 2018-07-23

Springer Nature

Journal: Nature Physics

Quartile SCImago

Quartile WOS

Impact factor: 19.6

ISSN: 17452473

DOI: 10.1038/s41567-018-0214-9

Copy DOI

General Physics and Astronomy

Abstract

Cell and gene damage caused by ionizing radiation has been studied for many years. It is accepted that DNA lesions (single- and double-strand breaks, for example) are induced by secondary species such as radicals, ions and the abundant low-energy secondary electrons generated by the primary radiation. Particularly harmful are dense ionization clusters of several ionization processes within a volume typical for the biomolecular system. Here we report the observation of a damage mechanism in the form of a non-local autoionizing process called intermolecular Coulombic decay (ICD). It directly involves DNA constituents or other organic molecules in an aqueous environment. The products are two energetic ions and three reactive secondary electrons that can cause further damage in their vicinity. Hydrogen-bonded complexes that consist of one tetrahydrofuran (THF) molecule—a surrogate of deoxyribose in the DNA backbone—and one water molecule are used as a model system. After electron impact ionization of the water molecule in the inner-valence shell the vacancy is filled by an outer-valence electron. The released energy is transferred across the hydrogen bridge and leads to ionization of the neighbouring THF molecule. This energy transfer from water to THF is faster than the otherwise occurring intermolecular proton transfer. The signature of the ICD reaction is identified in triple-coincidence measurements of both ions and one of the final state electrons. These results could improve the understanding of radiation damage in biological tissue. The authors study intermolecular Coulomb decay that occurs in a sample of THF and water in a reaction microscope employing triple-coincidence measurements of two ions and one electron. They find that ICD is a previously unconsidered effect between water and other organic molecules that are hydrogen-bonded, with ICD outpacing proton transfer.

By date By citations

Citations by journals

	2 4 6 8 10 12 14 16
Physical Review A	Physical Review A, 16, 18.6% Physical Review A 16 publications, 18.6%
Journal of Physical Chemistry Letters	Journal of Physical Chemistry Letters, 8, 9.3% Journal of Physical Chemistry Letters 8 publications, 9.3%
Journal of Chemical Physics	Journal of Chemical Physics, 8, 9.3% Journal of Chemical Physics 8 publications, 9.3%
Physical Chemistry Chemical Physics	Physical Chemistry Chemical Physics, 7, 8.14% Physical Chemistry Chemical Physics 7 publications, 8.14%
Physical Review Letters	Physical Review Letters, 6, 6.98% Physical Review Letters 6 publications, 6.98%
Nature Communications	Nature Communications, 5, 5.81% Nature Communications 5 publications, 5.81%
Journal of Physics B: Atomic, Molecular and Optical Physics	Journal of Physics B: Atomic, Molecular and Optical Physics, 2, 2.33% Journal of Physics B: Atomic, Molecular and Optical Physics 2 publications, 2.33%
Chinese Physics Letters	Chinese Physics Letters, 2, 2.33% Chinese Physics Letters 2 publications, 2.33%
Journal of Physical Chemistry A	Journal of Physical Chemistry A, 2, 2.33% Journal of Physical Chemistry A 2 publications, 2.33%
Journal of Chemical Theory and Computation	Journal of Chemical Theory and Computation, 2, 2.33% Journal of Chemical Theory and Computation 2 publications, 2.33%
Biophysica	Biophysica, 1, 1.16% Biophysica 1 publication, 1.16%
Physical Review Research	Physical Review Research, 1, 1.16% Physical Review Research 1 publication, 1.16%
Physical Review X	Physical Review X, 1, 1.16% Physical Review X 1 publication, 1.16%
Condensed Matter	Condensed Matter, 1, 1.16% Condensed Matter 1 publication, 1.16%
Nature Chemistry	Nature Chemistry, 1, 1.16% Nature Chemistry 1 publication, 1.16%
Nature Physics	Nature Physics, 1, 1.16% Nature Physics 1 publication, 1.16%
Chemical Physics	Chemical Physics, 1, 1.16% Chemical Physics 1 publication, 1.16%
Journal of Physics: Conference Series	Journal of Physics: Conference Series, 1, 1.16% Journal of Physics: Conference Series 1 publication, 1.16%
Chinese Physics B	Chinese Physics B, 1, 1.16% Chinese Physics B 1 publication, 1.16%
Nanotechnology	Nanotechnology, 1, 1.16% Nanotechnology 1 publication, 1.16%
Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms	Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, 1, 1.16% Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms 1 publication, 1.16%
Angewandte Chemie	Angewandte Chemie, 1, 1.16% Angewandte Chemie 1 publication, 1.16%
Angewandte Chemie - International Edition	Angewandte Chemie - International Edition, 1, 1.16% Angewandte Chemie - International Edition 1 publication, 1.16%
Chemistry - A European Journal	Chemistry - A European Journal, 1, 1.16% Chemistry - A European Journal 1 publication, 1.16%
Wiley Interdisciplinary Reviews: Computational Molecular Science	Wiley Interdisciplinary Reviews: Computational Molecular Science, 1, 1.16% Wiley Interdisciplinary Reviews: Computational Molecular Science 1 publication, 1.16%
Journal of Physical Chemistry C	Journal of Physical Chemistry C, 1, 1.16% Journal of Physical Chemistry C 1 publication, 1.16%
Chemical Reviews	Chemical Reviews, 1, 1.16% Chemical Reviews 1 publication, 1.16%
Topics in Applied Physics	Topics in Applied Physics, 1, 1.16% Topics in Applied Physics 1 publication, 1.16%
Optics Express	Optics Express, 1, 1.16% Optics Express 1 publication, 1.16%

	2 4 6 8 10 12 14 16

Citations by publishers

	5 10 15 20 25
American Physical Society (APS)	American Physical Society (APS), 24, 27.91% American Physical Society (APS) 24 publications, 27.91%
American Chemical Society (ACS)	American Chemical Society (ACS), 14, 16.28% American Chemical Society (ACS) 14 publications, 16.28%
American Institute of Physics (AIP)	American Institute of Physics (AIP), 8, 9.3% American Institute of Physics (AIP) 8 publications, 9.3%
Springer Nature	Springer Nature, 8, 9.3% Springer Nature 8 publications, 9.3%
IOP Publishing	IOP Publishing, 8, 9.3% IOP Publishing 8 publications, 9.3%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 7, 8.14% Royal Society of Chemistry (RSC) 7 publications, 8.14%
Wiley	Wiley, 4, 4.65% Wiley 4 publications, 4.65%
Elsevier	Elsevier, 3, 3.49% Elsevier 3 publications, 3.49%
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 2, 2.33% Multidisciplinary Digital Publishing Institute (MDPI) 2 publications, 2.33%
Optical Society of America	Optical Society of America, 1, 1.16% Optical Society of America 1 publication, 1.16%
Cambridge University Press	Cambridge University Press, 1, 1.16% Cambridge University Press 1 publication, 1.16%
	5 10 15 20 25

We do not take into account publications that without a DOI.
Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
Statistics recalculated weekly.

{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2018,2019,2020,2021,2022,2023,2024],"ids":[0,0,0,0,0,0,0],"codes":[0,0,0,0,0,0,0],"imageUrls":["","","","","","",""],"datasets":[{"label":"Citations number","data":[3,14,15,13,19,16,6],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["3.49","16.28","17.44","15.12","22.09","18.6","6.98"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Physical Review A","Journal of Physical Chemistry Letters","Journal of Chemical Physics","Physical Chemistry Chemical Physics","Physical Review Letters","Nature Communications","Journal of Physics B: Atomic, Molecular and Optical Physics","Chinese Physics Letters","Journal of Physical Chemistry A","Journal of Chemical Theory and Computation","Biophysica","Physical Review Research","Physical Review X","Condensed Matter","Nature Chemistry","Nature Physics","Chemical Physics","Journal of Physics: Conference Series","Chinese Physics B","Nanotechnology","Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms","Angewandte Chemie","Angewandte Chemie - International Edition","Chemistry - A European Journal","Wiley Interdisciplinary Reviews: Computational Molecular Science","Journal of Physical Chemistry C","Chemical Reviews","Topics in Applied Physics","Optics Express"],"ids":[12492,21963,544,1773,4343,3231,9735,22690,15255,58,27294,26813,10044,26994,17228,14887,11321,3333,6895,16187,3324,25450,19215,24708,22866,8859,13718,23023,8923],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/nrK64iXHTzj43wMrfN1ZoUQ0vanswGzWPN45K3jA_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/ARM4e6URKRsbRZvIF0vFis9DjxGloBjnBYJXbHmZ_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/nrK64iXHTzj43wMrfN1ZoUQ0vanswGzWPN45K3jA_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/LsKy6OnmmmRGcAU6CZgWQvNiP1polbaSLNrN7zqj_medium.webp","\/storage\/images\/resized\/LsKy6OnmmmRGcAU6CZgWQvNiP1polbaSLNrN7zqj_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/nrK64iXHTzj43wMrfN1ZoUQ0vanswGzWPN45K3jA_medium.webp","\/storage\/images\/resized\/nrK64iXHTzj43wMrfN1ZoUQ0vanswGzWPN45K3jA_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/LsKy6OnmmmRGcAU6CZgWQvNiP1polbaSLNrN7zqj_medium.webp","\/storage\/images\/resized\/LsKy6OnmmmRGcAU6CZgWQvNiP1polbaSLNrN7zqj_medium.webp","\/storage\/images\/resized\/LsKy6OnmmmRGcAU6CZgWQvNiP1polbaSLNrN7zqj_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/bypZPcr6C4twKiQVCUCGc0GF4cH6aUWmpClD3hsH_medium.webp"],"datasets":[{"label":"","data":[16,8,8,7,6,5,2,2,2,2,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[18.6,9.3,9.3,8.14,6.98,5.81,2.33,2.33,2.33,2.33,1.16,1.16,1.16,1.16,1.16,1.16,1.16,1.16,1.16,1.16,1.16,1.16,1.16,1.16,1.16,1.16,1.16,1.16,1.16],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["American Physical Society (APS)","American Chemical Society (ACS)","American Institute of Physics (AIP)","Springer Nature","IOP Publishing","Royal Society of Chemistry (RSC)","Wiley","Elsevier","Multidisciplinary Digital Publishing Institute (MDPI)","Optical Society of America","Cambridge University Press"],"ids":[1539,40,250,8,2075,123,11,17,202,375,1],"codes":[0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/nrK64iXHTzj43wMrfN1ZoUQ0vanswGzWPN45K3jA_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/ARM4e6URKRsbRZvIF0vFis9DjxGloBjnBYJXbHmZ_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/LsKy6OnmmmRGcAU6CZgWQvNiP1polbaSLNrN7zqj_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/bypZPcr6C4twKiQVCUCGc0GF4cH6aUWmpClD3hsH_medium.webp","\/storage\/images\/resized\/cF81zWlLdkmYekymGuDcSdvgBGNKaIDoMoeJtHS1_medium.webp"],"datasets":[{"label":"","data":[24,14,8,8,8,7,4,3,2,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[27.91,16.28,9.3,9.3,9.3,8.14,4.65,3.49,2.33,1.16,1.16],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}

Metrics

Cite this

GOST |

Cite this

GOST Copy

Ren X. et al. Experimental evidence for ultrafast intermolecular relaxation processes in hydrated biomolecules // Nature Physics. 2018. Vol. 14. No. 10. pp. 1062-1066.

GOST all authors (up to 50) Copy

Ren X., Wang E., Skitnevskaya A. D., Trofimov A., Gokhberg K., Dorn A. Experimental evidence for ultrafast intermolecular relaxation processes in hydrated biomolecules // Nature Physics. 2018. Vol. 14. No. 10. pp. 1062-1066.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1038/s41567-018-0214-9

UR - https://doi.org/10.1038%2Fs41567-018-0214-9

TI - Experimental evidence for ultrafast intermolecular relaxation processes in hydrated biomolecules

T2 - Nature Physics

AU - Ren, Xueguang

AU - Wang, Enliang

AU - Skitnevskaya, A D

AU - Trofimov, A.B.

AU - Gokhberg, Kirill

AU - Dorn, Alexander

PY - 2018

DA - 2018/07/23 00:00:00

PB - Springer Nature

SP - 1062-1066

IS - 10

VL - 14

SN - 1745-2473

ER -

BibTex |

Cite this

BibTex Copy

@article{2018_Ren,

author = {Xueguang Ren and Enliang Wang and A D Skitnevskaya and A.B. Trofimov and Kirill Gokhberg and Alexander Dorn},

title = {Experimental evidence for ultrafast intermolecular relaxation processes in hydrated biomolecules},

journal = {Nature Physics},

year = {2018},

volume = {14},

publisher = {Springer Nature},

month = {jul},

url = {https://doi.org/10.1038%2Fs41567-018-0214-9},

number = {10},

pages = {1062--1066},

doi = {10.1038/s41567-018-0214-9}

}

MLA

Cite this

MLA Copy

Ren, Xueguang, et al. “Experimental evidence for ultrafast intermolecular relaxation processes in hydrated biomolecules.” Nature Physics, vol. 14, no. 10, Jul. 2018, pp. 1062-1066. https://doi.org/10.1038%2Fs41567-018-0214-9.

Found error?

Publisher

Springer Nature

Journal

Nature Physics

Quartile SCImago

Quartile WOS

Impact factor

19.6

ISSN

17452473 (Print)

Labs

Laboratory of Quantum Chemical Modeling of Molecular Systems

Profiles