Open Access
Cross section measurements of 151Eu(3He,5n) reaction: new opportunities for medical alpha emitter 149Tb production
A N Moiseeva
1
,
R. A. Aliev
1, 2
,
V N Unezhev
1
,
V A Zagryadskiy
1
,
S T Latushkin
1
,
N. V. Aksenov
3
,
N S Gustova
3
,
M G Voronuk
3
,
G. Ya. Starodub
3
,
A. A. Ogloblin
1
Тип публикации: Journal Article
Дата публикации: 2020-01-16
scimago Q1
wos Q1
БС1
SJR: 0.874
CiteScore: 6.7
Impact factor: 3.9
ISSN: 20452322
PubMed ID:
31949230
Multidisciplinary
Краткое описание
Method for production of alpha emitter 149Tb by irradiation of 151Eu with 70 MeV 3He nuclei is proposed. For the first time, the cross sections for the formation of isotopes 149,150,151,152Tb were measured experimentally using a stack foil technique in the 3He particles energy range 70 → 12 MeV. The thick target yield of 149Tb is 39 MBq/μAh, or 230 MBq/μA 149Tb at saturation. The optimal energy range from the point of view of radioisotopic purity is 70 → 40 MeV. At these conditions about 150 MBq/μA 149Tb can be produced in 8 hours irradiation, which is sufficient for therapeutic applications. The main impurities are 150Tb (~100% in activity) and 151Tb (~30% in activity). The proposed method surpasses its counterparts by the high content of the target isotope in the natural mixture and the simplicity of the radiochemical separation of 149Tb from the bulk target material.
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ГОСТ
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Moiseeva A. N. et al. Cross section measurements of 151Eu(3He,5n) reaction: new opportunities for medical alpha emitter 149Tb production // Scientific Reports. 2020. Vol. 10. No. 1. 508
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Moiseeva A. N., Aliev R. A., Unezhev V. N., Zagryadskiy V. A., Latushkin S. T., Aksenov N. V., Gustova N. S., Voronuk M. G., Starodub G. Y., Ogloblin A. A. Cross section measurements of 151Eu(3He,5n) reaction: new opportunities for medical alpha emitter 149Tb production // Scientific Reports. 2020. Vol. 10. No. 1. 508
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TY - JOUR
DO - 10.1038/s41598-020-57436-6
UR - https://doi.org/10.1038/s41598-020-57436-6
TI - Cross section measurements of 151Eu(3He,5n) reaction: new opportunities for medical alpha emitter 149Tb production
T2 - Scientific Reports
AU - Moiseeva, A N
AU - Aliev, R. A.
AU - Unezhev, V N
AU - Zagryadskiy, V A
AU - Latushkin, S T
AU - Aksenov, N. V.
AU - Gustova, N S
AU - Voronuk, M G
AU - Starodub, G. Ya.
AU - Ogloblin, A. A.
PY - 2020
DA - 2020/01/16
PB - Springer Nature
IS - 1
VL - 10
PMID - 31949230
SN - 2045-2322
ER -
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BibTex (до 50 авторов)
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@article{2020_Moiseeva,
author = {A N Moiseeva and R. A. Aliev and V N Unezhev and V A Zagryadskiy and S T Latushkin and N. V. Aksenov and N S Gustova and M G Voronuk and G. Ya. Starodub and A. A. Ogloblin},
title = {Cross section measurements of 151Eu(3He,5n) reaction: new opportunities for medical alpha emitter 149Tb production},
journal = {Scientific Reports},
year = {2020},
volume = {10},
publisher = {Springer Nature},
month = {jan},
url = {https://doi.org/10.1038/s41598-020-57436-6},
number = {1},
pages = {508},
doi = {10.1038/s41598-020-57436-6}
}
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