том 9 издание 5 страницы 338-350

Targeting DNA topoisomerase II in cancer chemotherapy

Тип публикацииJournal Article
Дата публикации2009-04-20
SCImago Q1
Tоп 10% SCImago
WOS Q1
БС1
SJR22.814
CiteScore103.8
Impact factor66.8
ISSN1474175X, 14741768
General Environmental Science
General Earth and Planetary Sciences
Краткое описание
Recent molecular studies have expanded the biological contexts in which topoisomerase II (TOP2) has crucial functions, including DNA replication, transcription and chromosome segregation. Although the biological functions of TOP2 are important for ensuring genomic integrity, the ability to interfere with TOP2 and generate enzyme-mediated DNA damage is an effective strategy for cancer chemotherapy. The molecular tools that have allowed an understanding of the biological functions of TOP2 are also being applied to understanding the details of drug action. These studies promise refined targeting of TOP2 as an effective anticancer strategy.
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ГОСТ |
Цитировать
Nitiss J. L. Targeting DNA topoisomerase II in cancer chemotherapy // Nature Reviews Cancer. 2009. Vol. 9. No. 5. pp. 338-350.
ГОСТ со всеми авторами (до 50) Скопировать
Nitiss J. L. Targeting DNA topoisomerase II in cancer chemotherapy // Nature Reviews Cancer. 2009. Vol. 9. No. 5. pp. 338-350.
RIS |
Цитировать
TY - JOUR
DO - 10.1038/nrc2607
UR - https://doi.org/10.1038/nrc2607
TI - Targeting DNA topoisomerase II in cancer chemotherapy
T2 - Nature Reviews Cancer
AU - Nitiss, John L
PY - 2009
DA - 2009/04/20
PB - Springer Nature
SP - 338-350
IS - 5
VL - 9
PMID - 19377506
SN - 1474-175X
SN - 1474-1768
ER -
BibTex |
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BibTex (до 50 авторов) Скопировать
@article{2009_Nitiss,
author = {John L Nitiss},
title = {Targeting DNA topoisomerase II in cancer chemotherapy},
journal = {Nature Reviews Cancer},
year = {2009},
volume = {9},
publisher = {Springer Nature},
month = {apr},
url = {https://doi.org/10.1038/nrc2607},
number = {5},
pages = {338--350},
doi = {10.1038/nrc2607}
}
MLA
Цитировать
Nitiss, John L.. “Targeting DNA topoisomerase II in cancer chemotherapy.” Nature Reviews Cancer, vol. 9, no. 5, Apr. 2009, pp. 338-350. https://doi.org/10.1038/nrc2607.
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