Open Access
Open access
Springer Nature
Bone Research
,  volume 11 ,  issue 1 ,  publication number 61

Structure and function of the membrane microdomains in osteoclasts

Publication type: Journal Article
Publication date: 2023-11-21
Springer Nature
scimago Q1
wos Q1
SJR: 4.048
CiteScore: 23.3
Impact factor: 15.0
ISSN: 20954700, 20956231
Histology
Physiology
Endocrinology, Diabetes and Metabolism
Abstract

The cell membrane structure is closely related to the occurrence and progression of many metabolic bone diseases observed in the clinic and is an important target to the development of therapeutic strategies for these diseases. Strong experimental evidence supports the existence of membrane microdomains in osteoclasts (OCs). However, the potential membrane microdomains and the crucial mechanisms underlying their roles in OCs have not been fully characterized. Membrane microdomain components, such as scaffolding proteins and the actin cytoskeleton, as well as the roles of individual membrane proteins, need to be elucidated. In this review, we discuss the compositions and critical functions of membrane microdomains that determine the biological behavior of OCs through the three main stages of the OC life cycle.

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GOST |
Cite this
GOST Copy
Hou J. et al. Structure and function of the membrane microdomains in osteoclasts // Bone Research. 2023. Vol. 11. No. 1. 61
GOST all authors (up to 50) Copy
Hou J., Liu J., Huang Z., Wang Y., Yao H., Hu Z., Shi C., Xu J., Wang Q. Structure and function of the membrane microdomains in osteoclasts // Bone Research. 2023. Vol. 11. No. 1. 61
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1038/s41413-023-00294-5
UR - https://doi.org/10.1038/s41413-023-00294-5
TI - Structure and function of the membrane microdomains in osteoclasts
T2 - Bone Research
AU - Hou, Jialong
AU - Liu, Jian
AU - Huang, Zhixian
AU - Wang, Yining
AU - Yao, Hanbing
AU - Hu, Zhenxin
AU - Shi, Chengge
AU - Xu, Jiake
AU - Wang, Qingqing
PY - 2023
DA - 2023/11/21
PB - Springer Nature
IS - 1
VL - 11
PMID - 37989999
SN - 2095-4700
SN - 2095-6231
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2023_Hou,
author = {Jialong Hou and Jian Liu and Zhixian Huang and Yining Wang and Hanbing Yao and Zhenxin Hu and Chengge Shi and Jiake Xu and Qingqing Wang},
title = {Structure and function of the membrane microdomains in osteoclasts},
journal = {Bone Research},
year = {2023},
volume = {11},
publisher = {Springer Nature},
month = {nov},
url = {https://doi.org/10.1038/s41413-023-00294-5},
number = {1},
pages = {61},
doi = {10.1038/s41413-023-00294-5}
}