Journal of the Chemical Society Perkin Transactions 1, issue 8, pages 1061-1066

Total synthesis of naamine C and pyronaamidine, antitumor marine imidazole alkaloids

Seikou Nakamura ¹

Ikuo Kawasaki ¹

Miki Kunimura ¹

Miyuki Matsui ¹

Yoko Noma ¹

Masayuki Yamashita ¹

Shunsaku Ohta ¹

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Kyoto Pharmaceutical University, Misasagi Yamashinaku, Kyoto 607-8414, Japan |

Publication type: Journal Article

Publication date: 2002-03-19

Royal Society of Chemistry (RSC)

Journal: Journal of the Chemical Society Perkin Transactions 1

SJR: —

CiteScore: —

Impact factor: —

ISSN: 0300922X, 13645463, 14727781

DOI: 10.1039/b200845a

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General Medicine

Abstract

The first total synthesis of naamine C and pyronaamidine, highly substituted and cytotoxic imidazole marine alkaloids of a certain kind of sponge, was achieved through an eight-step reaction starting from 1-methyl-2-phenylthio-1H-imidazole.

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Publisher

Royal Society of Chemistry (RSC)

Journal

Journal of the Chemical Society Perkin Transactions 1

SJR

—

CiteScore

—

Impact factor

—

ISSN

0300922X (Print)

13645463 (Electronic)

14727781 (Print)

Total synthesis of naamine C and pyronaamidine, antitumor marine imidazole alkaloids

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