Synthesis of dopastin, a dopamine β-hydroxylase inhibitor of microbial origin

M. Ohno
H. Iinuma
N. Yagisawa
S Shibahara
Y Suhara
S. Kondo
K. MAEDA
H. Umezawa
Publication typeJournal Article
Publication date1973-01-01
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ISSN00224936
Molecular Medicine
Abstract
Dopastin has been synthesised from L-valinol by an 8-step procedure, in which the key stage involves oxaziran formation followed by hydrolysis with Dowex 50W, with retention of the absolute configuration of the starting material in the final product.
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GOST Copy
Ohno M. et al. Synthesis of dopastin, a dopamine β-hydroxylase inhibitor of microbial origin // Journal of the Chemical Society Chemical Communications. 1973. Vol. 4. pp. 147-148.
GOST all authors (up to 50) Copy
Ohno M., Iinuma H., Yagisawa N., Shibahara S., Suhara Y., Kondo S., MAEDA K., Umezawa H. Synthesis of dopastin, a dopamine β-hydroxylase inhibitor of microbial origin // Journal of the Chemical Society Chemical Communications. 1973. Vol. 4. pp. 147-148.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1039/c39730000147
UR - https://doi.org/10.1039/c39730000147
TI - Synthesis of dopastin, a dopamine β-hydroxylase inhibitor of microbial origin
T2 - Journal of the Chemical Society Chemical Communications
AU - Ohno, M.
AU - Iinuma, H.
AU - Yagisawa, N.
AU - Shibahara, S
AU - Suhara, Y
AU - Kondo, S.
AU - MAEDA, K.
AU - Umezawa, H.
PY - 1973
DA - 1973/01/01
PB - Royal Society of Chemistry (RSC)
SP - 147-148
IS - 4
SN - 0022-4936
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{1973_Ohno,
author = {M. Ohno and H. Iinuma and N. Yagisawa and S Shibahara and Y Suhara and S. Kondo and K. MAEDA and H. Umezawa},
title = {Synthesis of dopastin, a dopamine β-hydroxylase inhibitor of microbial origin},
journal = {Journal of the Chemical Society Chemical Communications},
year = {1973},
publisher = {Royal Society of Chemistry (RSC)},
month = {jan},
url = {https://doi.org/10.1039/c39730000147},
number = {4},
pages = {147--148},
doi = {10.1039/c39730000147}
}