volume 5 issue 5 pages 576-586

Novel 3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogs of curcumin: anticancer activity evaluation and mode of action study

Anuj Thakur 1
Sunny Manohar 1
Christian E Vélez Gerena 2
Beatriz Zayas 2
Vineet Kumar 3
Sanjay Malhotra 3
Diwan S. Rawat 1
Publication typeJournal Article
Publication date2014-02-11
SJR
CiteScore
Impact factor
ISSN20402503, 20402511
Organic Chemistry
Drug Discovery
Biochemistry
Pharmacology
Pharmaceutical Science
Molecular Medicine
Abstract

Piperidone-sulphonamide and curcumin based molecular hybrids were synthesised, which showed anti-cancer activity on 60 human tumor cell line panels and their inhibitory effect due to apoptosis.

Found 
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GOST |
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GOST Copy
Thakur A. et al. Novel 3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogs of curcumin: anticancer activity evaluation and mode of action study // MedChemComm. 2014. Vol. 5. No. 5. pp. 576-586.
GOST all authors (up to 50) Copy
Thakur A., Manohar S., Vélez Gerena C. E., Zayas B., Kumar V., Malhotra S., Rawat D. S. Novel 3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogs of curcumin: anticancer activity evaluation and mode of action study // MedChemComm. 2014. Vol. 5. No. 5. pp. 576-586.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1039/c3md00399j
UR - https://doi.org/10.1039/c3md00399j
TI - Novel 3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogs of curcumin: anticancer activity evaluation and mode of action study
T2 - MedChemComm
AU - Thakur, Anuj
AU - Manohar, Sunny
AU - Vélez Gerena, Christian E
AU - Zayas, Beatriz
AU - Kumar, Vineet
AU - Malhotra, Sanjay
AU - Rawat, Diwan S.
PY - 2014
DA - 2014/02/11
PB - Royal Society of Chemistry (RSC)
SP - 576-586
IS - 5
VL - 5
SN - 2040-2503
SN - 2040-2511
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2014_Thakur,
author = {Anuj Thakur and Sunny Manohar and Christian E Vélez Gerena and Beatriz Zayas and Vineet Kumar and Sanjay Malhotra and Diwan S. Rawat},
title = {Novel 3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogs of curcumin: anticancer activity evaluation and mode of action study},
journal = {MedChemComm},
year = {2014},
volume = {5},
publisher = {Royal Society of Chemistry (RSC)},
month = {feb},
url = {https://doi.org/10.1039/c3md00399j},
number = {5},
pages = {576--586},
doi = {10.1039/c3md00399j}
}
MLA
Cite this
MLA Copy
Thakur, Anuj, et al. “Novel 3,5-bis(arylidiene)-4-piperidone based monocarbonyl analogs of curcumin: anticancer activity evaluation and mode of action study.” MedChemComm, vol. 5, no. 5, Feb. 2014, pp. 576-586. https://doi.org/10.1039/c3md00399j.