volume 12 issue 7 pages 2142-2146

Stabilization of epigenetic states of CpG islands by local cooperation

Publication typeJournal Article
Publication date2016-02-23
SJR
CiteScore
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ISSN1742206X, 17422051
PubMed ID:  26923344
Molecular Biology
Biotechnology
Abstract

DNA methylation at CpG sites is an epigenetic mark that correlates with gene expresssion. Dense regions of CpG sites, so-called CpG islands, are often either fully methylated or fully unmethylated, hinting at a bistable dynamical process by which sites undergo coordinated methylation activity. We here explore a process by which CpG sites can protect others from becoming methylated, thereby re-enforcing the bistable dynamics.

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GOST Copy
Sormani G. et al. Stabilization of epigenetic states of CpG islands by local cooperation // Molecular BioSystems. 2016. Vol. 12. No. 7. pp. 2142-2146.
GOST all authors (up to 50) Copy
Sormani G., Haerter J. O., Lövkvist C., Sneppen K. Stabilization of epigenetic states of CpG islands by local cooperation // Molecular BioSystems. 2016. Vol. 12. No. 7. pp. 2142-2146.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1039/c6mb00044d
UR - https://doi.org/10.1039/c6mb00044d
TI - Stabilization of epigenetic states of CpG islands by local cooperation
T2 - Molecular BioSystems
AU - Sormani, Giulia
AU - Haerter, J. O.
AU - Lövkvist, Cecilia
AU - Sneppen, Kim
PY - 2016
DA - 2016/02/23
PB - Royal Society of Chemistry (RSC)
SP - 2142-2146
IS - 7
VL - 12
PMID - 26923344
SN - 1742-206X
SN - 1742-2051
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2016_Sormani,
author = {Giulia Sormani and J. O. Haerter and Cecilia Lövkvist and Kim Sneppen},
title = {Stabilization of epigenetic states of CpG islands by local cooperation},
journal = {Molecular BioSystems},
year = {2016},
volume = {12},
publisher = {Royal Society of Chemistry (RSC)},
month = {feb},
url = {https://doi.org/10.1039/c6mb00044d},
number = {7},
pages = {2142--2146},
doi = {10.1039/c6mb00044d}
}
MLA
Cite this
MLA Copy
Sormani, Giulia, et al. “Stabilization of epigenetic states of CpG islands by local cooperation.” Molecular BioSystems, vol. 12, no. 7, Feb. 2016, pp. 2142-2146. https://doi.org/10.1039/c6mb00044d.