From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release
Sylvain A Jacques
1
,
Geoffray Leriche
1
,
Michel Mosser
1
,
Marc Nothisen
2
,
Christian Muller
3
,
JEAN-SERGE REMY
2
,
Alain Wagner
1
Publication type: Journal Article
Publication date: 2016-05-06
scimago Q2
wos Q2
SJR: 0.600
CiteScore: 5.2
Impact factor: 2.7
ISSN: 14770520, 14770539
PubMed ID:
27169758
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
pH-Sensitive linkers designed to undergo selective hydrolysis at acidic pH compared to physiological pH can be used for the selective release of therapeutics at their site of action.
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Metrics
29
Total citations:
29
Citations from 2024:
6
(20.69%)
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MLA
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GOST
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Jacques S. A. et al. From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release // Organic and Biomolecular Chemistry. 2016. Vol. 14. No. 21. pp. 4794-4803.
GOST all authors (up to 50)
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Jacques S. A., Leriche G., Mosser M., Nothisen M., Muller C., REMY J., Wagner A. From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release // Organic and Biomolecular Chemistry. 2016. Vol. 14. No. 21. pp. 4794-4803.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1039/c6ob00846a
UR - https://doi.org/10.1039/c6ob00846a
TI - From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release
T2 - Organic and Biomolecular Chemistry
AU - Jacques, Sylvain A
AU - Leriche, Geoffray
AU - Mosser, Michel
AU - Nothisen, Marc
AU - Muller, Christian
AU - REMY, JEAN-SERGE
AU - Wagner, Alain
PY - 2016
DA - 2016/05/06
PB - Royal Society of Chemistry (RSC)
SP - 4794-4803
IS - 21
VL - 14
PMID - 27169758
SN - 1477-0520
SN - 1477-0539
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2016_Jacques,
author = {Sylvain A Jacques and Geoffray Leriche and Michel Mosser and Marc Nothisen and Christian Muller and JEAN-SERGE REMY and Alain Wagner},
title = {From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release},
journal = {Organic and Biomolecular Chemistry},
year = {2016},
volume = {14},
publisher = {Royal Society of Chemistry (RSC)},
month = {may},
url = {https://doi.org/10.1039/c6ob00846a},
number = {21},
pages = {4794--4803},
doi = {10.1039/c6ob00846a}
}
Cite this
MLA
Copy
Jacques, Sylvain A., et al. “From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linkers for biospecific endosomal release.” Organic and Biomolecular Chemistry, vol. 14, no. 21, May. 2016, pp. 4794-4803. https://doi.org/10.1039/c6ob00846a.