Organic Chemistry Frontiers, volume 5, issue 16, pages 2427-2431

1,4-Dithiothreitol mediated cleavage of the acetal and ketal type of diol protecting groups

Yan Liu ¹

Jing Zeng ¹

Jiuchang Sun ¹

Lei Cai ¹

Yueqi Zhao ¹

Fang Jing ¹

Hu Bo ¹

Penghua Shu ¹

Lingkui Meng ¹

Qian Wan ^{1, 2}

Show full list: 12 authors

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Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan, Hubei, China |

Institute of Brain Research, Huazhong University of Science and Technology, China |

Publication type: Journal Article

Publication date: 2018-03-27

Royal Society of Chemistry (RSC)

Journal: Organic Chemistry Frontiers

scimago Q1

SJR: 1.016

CiteScore: 7.8

Impact factor: 4.6

ISSN: 20524110, 20524129

DOI: 10.1039/c8qo00247a

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Organic Chemistry

Abstract

An efficient deprotection of the ketal and acetal type protecting groups has been achieved with Brønsted acid as a catalyst and 1,4-dithiothreitol as a ketal or acetal exchange reagent.

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Publisher

Royal Society of Chemistry (RSC)

Journal

Organic Chemistry Frontiers

scimago Q1

SJR

1.016

CiteScore

7.8

Impact factor

4.6

ISSN

20524110 (Print)

20524129 (Electronic)

1,4-Dithiothreitol mediated cleavage of the acetal and ketal type of diol protecting groups

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