Medicinal chemistry of the myeloid C-type lectin receptors Mincle, Langerin, and DC-SIGN
Publication type: Journal Article
Publication date: 2021-09-16
scimago Q1
wos Q2
SJR: 0.841
CiteScore: 5.6
Impact factor: 3.6
ISSN: 26328682
PubMed ID:
35024612
Organic Chemistry
Drug Discovery
Biochemistry
Pharmacology
Pharmaceutical Science
Molecular Medicine
Abstract
In their role as pattern-recognition receptors on cells of the innate immune system, myeloid C-type lectin receptors (CLRs) assume important biological functions related to immunity, homeostasis, and cancer. As such, this family of receptors represents an appealing target for therapeutic interventions for modulating the outcome of many pathological processes, in particular related to infectious diseases. This review summarizes the current state of research into glycomimetic or drug-like small molecule ligands for the CLRs Mincle, Langerin, and DC-SIGN, which have potential therapeutic applications in vaccine research and anti-infective therapy.
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Total citations:
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Citations from 2024:
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(50%)
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GOST
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Cramer J. Medicinal chemistry of the myeloid C-type lectin receptors Mincle, Langerin, and DC-SIGN // RSC Medicinal Chemistry. 2021. Vol. 12. No. 12. pp. 1985-2000.
GOST all authors (up to 50)
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Cramer J. Medicinal chemistry of the myeloid C-type lectin receptors Mincle, Langerin, and DC-SIGN // RSC Medicinal Chemistry. 2021. Vol. 12. No. 12. pp. 1985-2000.
Cite this
RIS
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TY - JOUR
DO - 10.1039/d1md00238d
UR - https://xlink.rsc.org/?DOI=D1MD00238D
TI - Medicinal chemistry of the myeloid C-type lectin receptors Mincle, Langerin, and DC-SIGN
T2 - RSC Medicinal Chemistry
AU - Cramer, Jonathan
PY - 2021
DA - 2021/09/16
PB - Royal Society of Chemistry (RSC)
SP - 1985-2000
IS - 12
VL - 12
PMID - 35024612
SN - 2632-8682
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Cramer,
author = {Jonathan Cramer},
title = {Medicinal chemistry of the myeloid C-type lectin receptors Mincle, Langerin, and DC-SIGN},
journal = {RSC Medicinal Chemistry},
year = {2021},
volume = {12},
publisher = {Royal Society of Chemistry (RSC)},
month = {sep},
url = {https://xlink.rsc.org/?DOI=D1MD00238D},
number = {12},
pages = {1985--2000},
doi = {10.1039/d1md00238d}
}
Cite this
MLA
Copy
Cramer, Jonathan. “Medicinal chemistry of the myeloid C-type lectin receptors Mincle, Langerin, and DC-SIGN.” RSC Medicinal Chemistry, vol. 12, no. 12, Sep. 2021, pp. 1985-2000. https://xlink.rsc.org/?DOI=D1MD00238D.