Organic and Biomolecular Chemistry, volume 19, issue 45, pages 9797-9808

Ring closing metathesis for the construction of carbazole and indole-fused natural products

Publication typeJournal Article
Publication date2021-10-11
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor3.2
ISSN14770520, 14770539
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
The synthesis and functionalization of carbazole ring systems have received considerable attention in organic synthesis due to their widespread occurrence in biologically active compounds. One of the classical methods for the synthesis of carbazoles involves C-C bond formation of a biaryl amine moiety by oxidizing agents. Over the last few years, various new strategies have evolved for the synthesis of carbazole ring systems. During the past two decades, ring-closing metathesis (RCM) based approaches have been efficiently employed for the synthesis of nitrogen containing heteroaromatic systems including carbazoles. Herein, we discuss the construction of carbazole ring systems using RCM and the application of RCM based methods in the preparation of other indole-fused heterocycles. The application of these methods in the synthesis of carbazole alkaloids and bioactive indole-fused natural products has been discussed to highlight the importance of RCM in total synthesis.

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GOST |
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GOST Copy
Mandal T., Mandal T., Dash J. Ring closing metathesis for the construction of carbazole and indole-fused natural products // Organic and Biomolecular Chemistry. 2021. Vol. 19. No. 45. pp. 9797-9808.
GOST all authors (up to 50) Copy
Mandal T., Mandal T., Dash J. Ring closing metathesis for the construction of carbazole and indole-fused natural products // Organic and Biomolecular Chemistry. 2021. Vol. 19. No. 45. pp. 9797-9808.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1039/d1ob01471d
UR - https://doi.org/10.1039/d1ob01471d
TI - Ring closing metathesis for the construction of carbazole and indole-fused natural products
T2 - Organic and Biomolecular Chemistry
AU - Mandal, T.
AU - Dash, Jyotirmayee
AU - Mandal, Tirtha
PY - 2021
DA - 2021/10/11 00:00:00
PB - Royal Society of Chemistry (RSC)
SP - 9797-9808
IS - 45
VL - 19
SN - 1477-0520
SN - 1477-0539
ER -
BibTex |
Cite this
BibTex Copy
@article{2021_Mandal,
author = {T. Mandal and Jyotirmayee Dash and Tirtha Mandal},
title = {Ring closing metathesis for the construction of carbazole and indole-fused natural products},
journal = {Organic and Biomolecular Chemistry},
year = {2021},
volume = {19},
publisher = {Royal Society of Chemistry (RSC)},
month = {oct},
url = {https://doi.org/10.1039/d1ob01471d},
number = {45},
pages = {9797--9808},
doi = {10.1039/d1ob01471d}
}
MLA
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MLA Copy
Mandal, T., et al. “Ring closing metathesis for the construction of carbazole and indole-fused natural products.” Organic and Biomolecular Chemistry, vol. 19, no. 45, Oct. 2021, pp. 9797-9808. https://doi.org/10.1039/d1ob01471d.
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