A DNA origami nanostructure embedded with NQO1-activated prodrugs for precision drug delivery
Publication type: Journal Article
Publication date: 2023-01-01
scimago Q1
wos Q2
SJR: 1.037
CiteScore: 7.4
Impact factor: 4.2
ISSN: 13597345, 1364548X
PubMed ID:
36594872
Abstract
A rectangle DNA origami nanostructure equipped with doxorubicin-derived prodrugs targeting a tumor cell-specific enzyme (NQO1) is constructed. Combining the high prodrug payload of DNA origami and NQO1-activated chemotherapy, this nanosystem presents therapeutic selectivity for NQO1-overexpressing MCF-7 cells over healthy L02 cells, offering a potent strategy for precision cancer therapy.
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Metrics
11
Total citations:
11
Citations from 2024:
9
(81.81%)
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MLA
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GOST
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He Z. et al. A DNA origami nanostructure embedded with NQO1-activated prodrugs for precision drug delivery // Chemical Communications. 2023. Vol. 59. No. 7. pp. 912-915.
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He Z., Xiang W., FAN Q., Wang L., Chao J. A DNA origami nanostructure embedded with NQO1-activated prodrugs for precision drug delivery // Chemical Communications. 2023. Vol. 59. No. 7. pp. 912-915.
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RIS
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TY - JOUR
DO - 10.1039/d2cc06367k
UR - https://xlink.rsc.org/?DOI=D2CC06367K
TI - A DNA origami nanostructure embedded with NQO1-activated prodrugs for precision drug delivery
T2 - Chemical Communications
AU - He, Zhimei
AU - Xiang, Wenjie
AU - FAN, QIN
AU - Wang, Lianhui
AU - Chao, Jie
PY - 2023
DA - 2023/01/01
PB - Royal Society of Chemistry (RSC)
SP - 912-915
IS - 7
VL - 59
PMID - 36594872
SN - 1359-7345
SN - 1364-548X
ER -
Cite this
BibTex (up to 50 authors)
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@article{2023_He,
author = {Zhimei He and Wenjie Xiang and QIN FAN and Lianhui Wang and Jie Chao},
title = {A DNA origami nanostructure embedded with NQO1-activated prodrugs for precision drug delivery},
journal = {Chemical Communications},
year = {2023},
volume = {59},
publisher = {Royal Society of Chemistry (RSC)},
month = {jan},
url = {https://xlink.rsc.org/?DOI=D2CC06367K},
number = {7},
pages = {912--915},
doi = {10.1039/d2cc06367k}
}
Cite this
MLA
Copy
He, Zhimei, et al. “A DNA origami nanostructure embedded with NQO1-activated prodrugs for precision drug delivery.” Chemical Communications, vol. 59, no. 7, Jan. 2023, pp. 912-915. https://xlink.rsc.org/?DOI=D2CC06367K.
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