Synthesis of quinoxaline derivatives via aromatic nucleophilic substitution of hydrogen
Aleksandra Zasada
1, 2
,
Jakub Brześkiewicz
1
,
Damian Antoniak
1, 3
,
Małgorzata Bechcicka
1
,
Rafał Loska
1
,
Mieczysław Mąkosza
1
Publication type: Journal Article
Publication date: 2023-01-01
scimago Q2
wos Q2
SJR: 0.600
CiteScore: 5.2
Impact factor: 2.7
ISSN: 14770520, 14770539
PubMed ID:
36515404
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
The electrophilic nature of quinoxaline has been explored in the vicarious nucleophilic substitution (VNS) of hydrogen with various carbanions as nucleophiles in an attempt to develop a general method for functionalizing the heterocyclic ring. Only poorly stabilized nitrile carbanions were found to give the VNS products. 2-Chloroquinoxaline gave products of SNAr of chlorine preferentially. A variety of quinoxaline derivatives containing cyanoalkyl, sulfonylalkyl, benzyl or ester substituents, including fluorinated ones, have been prepared in the VNS reactions with quinoxaline N-oxide.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
|
|
|
ChemistrySelect
2 publications, 50%
|
|
|
Chemistry - A European Journal
1 publication, 25%
|
|
|
ChemSusChem
1 publication, 25%
|
|
|
1
2
|
Publishers
|
1
2
3
4
|
|
|
Wiley
4 publications, 100%
|
|
|
1
2
3
4
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
4
Total citations:
4
Citations from 2024:
3
(75%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Zasada A. et al. Synthesis of quinoxaline derivatives via aromatic nucleophilic substitution of hydrogen // Organic and Biomolecular Chemistry. 2023. Vol. 21. No. 5. pp. 994-999.
GOST all authors (up to 50)
Copy
Zasada A., Brześkiewicz J., Antoniak D., Bechcicka M., Loska R., Mąkosza M. Synthesis of quinoxaline derivatives via aromatic nucleophilic substitution of hydrogen // Organic and Biomolecular Chemistry. 2023. Vol. 21. No. 5. pp. 994-999.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1039/d2ob02016e
UR - https://xlink.rsc.org/?DOI=D2OB02016E
TI - Synthesis of quinoxaline derivatives via aromatic nucleophilic substitution of hydrogen
T2 - Organic and Biomolecular Chemistry
AU - Zasada, Aleksandra
AU - Brześkiewicz, Jakub
AU - Antoniak, Damian
AU - Bechcicka, Małgorzata
AU - Loska, Rafał
AU - Mąkosza, Mieczysław
PY - 2023
DA - 2023/01/01
PB - Royal Society of Chemistry (RSC)
SP - 994-999
IS - 5
VL - 21
PMID - 36515404
SN - 1477-0520
SN - 1477-0539
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2023_Zasada,
author = {Aleksandra Zasada and Jakub Brześkiewicz and Damian Antoniak and Małgorzata Bechcicka and Rafał Loska and Mieczysław Mąkosza},
title = {Synthesis of quinoxaline derivatives via aromatic nucleophilic substitution of hydrogen},
journal = {Organic and Biomolecular Chemistry},
year = {2023},
volume = {21},
publisher = {Royal Society of Chemistry (RSC)},
month = {jan},
url = {https://xlink.rsc.org/?DOI=D2OB02016E},
number = {5},
pages = {994--999},
doi = {10.1039/d2ob02016e}
}
Cite this
MLA
Copy
Zasada, Aleksandra, et al. “Synthesis of quinoxaline derivatives via aromatic nucleophilic substitution of hydrogen.” Organic and Biomolecular Chemistry, vol. 21, no. 5, Jan. 2023, pp. 994-999. https://xlink.rsc.org/?DOI=D2OB02016E.
Profiles