Total Synthesis of Lamellarin G Trimethyl Ether through Enaminone Cyclocondensation
Publication type: Journal Article
Publication date: 2023-06-29
scimago Q2
wos Q2
SJR: 0.600
CiteScore: 5.2
Impact factor: 2.7
ISSN: 14770520, 14770539
PubMed ID:
37435698
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A synthesis of pyrrolo[2,1-a]isoquinolines based on intramolecular condensation of an enaminone intermediate obtained by C-acylation of an N-alkylated 6,7-dimethoxy-1-methyl-3,4-dihydroisoquinolinium salt was developed. This methodology was further applied to the total synthesis of lamellarin G trimethyl ether from commercially available starting materials compatible with xylochemistry with an overall yield of 26% in 7 steps based on homoveratrylamine.
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7
Total citations:
7
Citations from 2024:
6
(85.71%)
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GOST
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Šachlevičiūtė U. et al. Total Synthesis of Lamellarin G Trimethyl Ether through Enaminone Cyclocondensation // Organic and Biomolecular Chemistry. 2023. Vol. 21. No. 29. pp. 5997-6007.
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Šachlevičiūtė U., Kleizienė N., Bieliauskas A., Šačkus A., Opatz T. Total Synthesis of Lamellarin G Trimethyl Ether through Enaminone Cyclocondensation // Organic and Biomolecular Chemistry. 2023. Vol. 21. No. 29. pp. 5997-6007.
Cite this
RIS
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TY - JOUR
DO - 10.1039/d3ob00870c
UR - https://xlink.rsc.org/?DOI=D3OB00870C
TI - Total Synthesis of Lamellarin G Trimethyl Ether through Enaminone Cyclocondensation
T2 - Organic and Biomolecular Chemistry
AU - Šachlevičiūtė, Urtė
AU - Kleizienė, Neringa
AU - Bieliauskas, Aurimas
AU - Šačkus, Algirdas
AU - Opatz, Till
PY - 2023
DA - 2023/06/29
PB - Royal Society of Chemistry (RSC)
SP - 5997-6007
IS - 29
VL - 21
PMID - 37435698
SN - 1477-0520
SN - 1477-0539
ER -
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BibTex (up to 50 authors)
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@article{2023_Šachlevičiūtė,
author = {Urtė Šachlevičiūtė and Neringa Kleizienė and Aurimas Bieliauskas and Algirdas Šačkus and Till Opatz},
title = {Total Synthesis of Lamellarin G Trimethyl Ether through Enaminone Cyclocondensation},
journal = {Organic and Biomolecular Chemistry},
year = {2023},
volume = {21},
publisher = {Royal Society of Chemistry (RSC)},
month = {jun},
url = {https://xlink.rsc.org/?DOI=D3OB00870C},
number = {29},
pages = {5997--6007},
doi = {10.1039/d3ob00870c}
}
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MLA
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Šachlevičiūtė, Urtė, et al. “Total Synthesis of Lamellarin G Trimethyl Ether through Enaminone Cyclocondensation.” Organic and Biomolecular Chemistry, vol. 21, no. 29, Jun. 2023, pp. 5997-6007. https://xlink.rsc.org/?DOI=D3OB00870C.
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