Rapid formation of N^ε-(carboxymethyl)lysine (CML) from ribose depends on glyoxal production by oxidation

Hikari Sugawa ¹

Tsuyoshi Ikeda ²

Yuki Tominaga ¹

Nana Katsuta ³

Ryoji Nagai ¹

Department of Food and Life Sciences, School of Agriculture, Tokai University, Japan |

Faculty of Pharmaceutical Sciences, Sojo University, Japan |

Research Institute of Agriculture, Tokai University, Japan |

Publication type: Journal Article

Publication date: 2024-09-18

Royal Society of Chemistry (RSC)

Journal: RSC Chemical Biology

scimago Q1

SJR: 1.144

CiteScore: 6.1

Impact factor: 4.2

ISSN: 26330679

DOI: 10.1039/d4cb00183d

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PubMed ID: 39323732

Abstract

Ribose undergoes auto-oxidation and oxidative cleavage between C-2 and C-3 to generate GO and enhance CML accumulation.

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Publisher

Royal Society of Chemistry (RSC)

Journal

scimago Q1

SJR

1.144

CiteScore

6.1

Impact factor

4.2

ISSN

26330679 (Electronic)

Rapid formation of Nε-(carboxymethyl)lysine (CML) from ribose depends on glyoxal production by oxidation