New Journal of Chemistry, volume 48, issue 29, pages 12947-12959

The short route to chalcogenurea-substituted 3a,6-epoxyisoindoles via an intramolecular Diels-Alder furan (IMDAF) reaction. Antibacterial and antifungal activity

Dmitriy F. Mertsalov ¹

Dmitriy M. Shchevnikov ¹

Lala V Lovtsevich ¹

Roman G. Novikov ²

Victor N. Khrustalev ^{1, 3}

Mikhail S. Grigoriev ⁴

Anna A Romanycheva ⁵

Anton A Shetnev ⁶

Olga P Bychkova ⁷

Alexey S Trenin ⁷

Vladimir P. Zaytsev ¹

Show full list: 11 authors

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RUDN University, 6 Miklukho-Maklaya St., Moscow 117198, Russian Federation |

V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilov St., Moscow, 119991, Russian Federation |

Zelinsky Institute of Organic Chemistry of RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation |

⁴

Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninsky pr. 31, bld. 4, 119071, Moscow, Russian Federation |

⁵

Pharmaceutical Technology Transfer Center, Yaroslavl State Pedagogical University named after K. D. Ushinsky, 108/1 Republican St., 150000, Yaroslavl, Russian Federation |

⁶

Moscow Institute of Physics and Technology 1 “A” Kerchenskaya St., Moscow, 117303, Russian Federation |

⁷

Gause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russian Federation |

Publication type: Journal Article

Publication date: 2024-07-01

Royal Society of Chemistry (RSC)

Journal: New Journal of Chemistry

scimago Q2

SJR: 0.521

CiteScore: 5.3

Impact factor: 2.7

ISSN: 11440546, 13699261

DOI: 10.1039/d4nj01174k

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Abstract

A concise preparative IMDAF strategy for the synthesis of chalcogenurea-substituted 3a,6-epoxyisoindoles, which display antifungal and antibacterial activity, starting from readily available materials was proposed.

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Publisher

Royal Society of Chemistry (RSC)

Journal

New Journal of Chemistry

scimago Q2

SJR

0.521

CiteScore

5.3

Impact factor

2.7

ISSN

11440546 (Print)

13699261 (Electronic)

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