TiF₄-mediated, one-pot, reductive amination of carboxylic acids with borane–ammonia

Madison J. Snyder ¹

Abdulkhaliq A Alawaed ¹

Chunge Li ¹

Samantha Pacentine ¹

Henry J. Hamann ¹

P Veeraraghavan Ramachandran ¹

Herbert C. Brown Center for Borane Research, Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA |

Publication type: Journal Article

Publication date: 2024-09-30

Royal Society of Chemistry (RSC)

Journal: RSC Advances

scimago Q1

SJR: 0.715

CiteScore: 7.5

Impact factor: 3.9

ISSN: 20462069

DOI: 10.1039/d4ra05888g

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Abstract

Reductive alkylation of amines with carboxylic acids is achieved using BH₃–NH₃ and TiF₄, yielding free amines or their borane-complexes.

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Publisher

Royal Society of Chemistry (RSC)

Journal

scimago Q1

SJR

0.715

CiteScore

7.5

Impact factor

3.9

ISSN

20462069 (Print, Electronic)

TiF4-mediated, one-pot, reductive amination of carboxylic acids with borane–ammonia