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Open access
Chemical Science, volume 16, issue 6, pages 2830-2836

Radical trifluoromethoxylation of fluorinated alkenes for accessing difluoro(trifluoromethoxy)methyl groups

Koki Kawai 1
Mai Usui 2
Sota Ikawa 2
Naoyuki Hoshiya 3
Yosuke Kishikawa 3
1
 
Department of Nanopharmaceutical Sciences, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan
2
 
Department of Engineering, Nagoya Institute of Technology, Gokiso, Showa-Ku, Nagoya 466-8555, Japan
3
 
Technology and Innovation Center, DAIKIN Industries, Ltd, 1-1 Nishi-Hitotsuya, Settsu, Osaka 566-8585, Japan
Publication typeJournal Article
Publication date2025-01-13
Journal: Chemical Science
scimago Q1
SJR2.333
CiteScore14.4
Impact factor7.6
ISSN20416520, 20416539
Abstract

In this study, we explore the potential of the difluoro(trifluoromethoxy)methyl group, CF2–O–CF3, an underexplored but promising structural analog of the trifluoromethoxy group (OCF3).

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