Royal Society of Chemistry (RSC)
Organic and Biomolecular Chemistry
,  том 8 ,  издание 2 ,  страницы 391-397

Nucleoside and nucleotide analogues by catalyst free Huisgen nitrile oxide-alkyne 1,3-dipolar cycloaddition.

Тип публикации: Journal Article
Дата публикации: 2010-01-01
Royal Society of Chemistry (RSC)
SCImago Q2
WOS Q2
БС1
SJR: 0.475
CiteScore: 4.8
Impact factor: 2.8
ISSN: 14770520, 14770539
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Краткое описание
An efficient, catalyst free, 1,3-dipolar cycloaddition strategy to conjugate nucleosides and nucleotides with isoxazoles under atmospheric conditions and in an aqueous environment is reported. The protocol involves chloramine-T as a practical reagent to induce in situ nitrile oxide formation and the alkyne partner is attached to the sugar residue or the nucleobase. The reactions are regiospecific, fast and high yielding.
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Algay V., Singh I., Heaney F. Nucleoside and nucleotide analogues by catalyst free Huisgen nitrile oxide-alkyne 1,3-dipolar cycloaddition. // Organic and Biomolecular Chemistry. 2010. Vol. 8. No. 2. pp. 391-397.
ГОСТ со всеми авторами (до 50) Скопировать
Algay V., Singh I., Heaney F. Nucleoside and nucleotide analogues by catalyst free Huisgen nitrile oxide-alkyne 1,3-dipolar cycloaddition. // Organic and Biomolecular Chemistry. 2010. Vol. 8. No. 2. pp. 391-397.
RIS |
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RIS Скопировать
TY - JOUR
DO - 10.1039/B917450H
UR - https://doi.org/10.1039/B917450H
TI - Nucleoside and nucleotide analogues by catalyst free Huisgen nitrile oxide-alkyne 1,3-dipolar cycloaddition.
T2 - Organic and Biomolecular Chemistry
AU - Algay, Virginie
AU - Singh, Ishwar
AU - Heaney, F.
PY - 2010
DA - 2010/01/01
PB - Royal Society of Chemistry (RSC)
SP - 391-397
IS - 2
VL - 8
PMID - 20066275
SN - 1477-0520
SN - 1477-0539
ER -
BibTex |
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@article{2010_Algay,
author = {Virginie Algay and Ishwar Singh and F. Heaney},
title = {Nucleoside and nucleotide analogues by catalyst free Huisgen nitrile oxide-alkyne 1,3-dipolar cycloaddition.},
journal = {Organic and Biomolecular Chemistry},
year = {2010},
volume = {8},
publisher = {Royal Society of Chemistry (RSC)},
month = {jan},
url = {https://doi.org/10.1039/B917450H},
number = {2},
pages = {391--397},
doi = {10.1039/B917450H}
}
MLA
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Algay, Virginie, et al. “Nucleoside and nucleotide analogues by catalyst free Huisgen nitrile oxide-alkyne 1,3-dipolar cycloaddition..” Organic and Biomolecular Chemistry, vol. 8, no. 2, Jan. 2010, pp. 391-397. https://doi.org/10.1039/B917450H.
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