Supra-amphiphilic aggregates formed by p-sulfonatocalix[4]arenes and the antipsychotic drug chlorpromazine.
Тип публикации: Journal Article
Дата публикации: 2013-12-11
SCImago Q2
WOS Q2
БС1
SJR: 0.667
CiteScore: 5.2
Impact factor: 2.9
ISSN: 1744683X, 17446848
PubMed ID:
24652226
General Chemistry
Condensed Matter Physics
Краткое описание
We report here a supramolecular strategy to directly assemble the small molecular antipsychotic drug chlorpromazine (CPZ) into nanostructures, induced by p-sulfonatocalix[4]arene (SC4A) and p-sulfonatocalix[4]arene tetraheptyl ether (SC4AH), with high drug loading efficiencies of 61% and 46%, respectively. The binary host-guest assembly process was monitored using optical transmittance measurements, and the size and morphology of these two kinds of supra-amphiphilic assemblies were identified using a combination of light scattering and high-resolution transmission electron microscopy, which showed solid spherical micelles. This strategy presents new opportunities for the development of high loading drug-containing carriers with easy processability for drug delivery.
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ГОСТ
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Qin Z. et al. Supra-amphiphilic aggregates formed by p-sulfonatocalix[4]arenes and the antipsychotic drug chlorpromazine. // Soft Matter. 2013. Vol. 10. No. 13. pp. 2253-2263.
ГОСТ со всеми авторами (до 50)
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Qin Z., Guo D., Gao X., Liu Yu. Supra-amphiphilic aggregates formed by p-sulfonatocalix[4]arenes and the antipsychotic drug chlorpromazine. // Soft Matter. 2013. Vol. 10. No. 13. pp. 2253-2263.
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RIS
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TY - JOUR
DO - 10.1039/C3SM52866A
UR - https://doi.org/10.1039/C3SM52866A
TI - Supra-amphiphilic aggregates formed by p-sulfonatocalix[4]arenes and the antipsychotic drug chlorpromazine.
T2 - Soft Matter
AU - Qin, Zhanbin
AU - Guo, Dong-Sheng
AU - Gao, Xiao-ning
AU - Liu, Yu
PY - 2013
DA - 2013/12/11
PB - Royal Society of Chemistry (RSC)
SP - 2253-2263
IS - 13
VL - 10
PMID - 24652226
SN - 1744-683X
SN - 1744-6848
ER -
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BibTex (до 50 авторов)
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@article{2013_Qin,
author = {Zhanbin Qin and Dong-Sheng Guo and Xiao-ning Gao and Yu Liu},
title = {Supra-amphiphilic aggregates formed by p-sulfonatocalix[4]arenes and the antipsychotic drug chlorpromazine.},
journal = {Soft Matter},
year = {2013},
volume = {10},
publisher = {Royal Society of Chemistry (RSC)},
month = {dec},
url = {https://doi.org/10.1039/C3SM52866A},
number = {13},
pages = {2253--2263},
doi = {10.1039/C3SM52866A}
}
Цитировать
MLA
Скопировать
Qin, Zhanbin, et al. “Supra-amphiphilic aggregates formed by p-sulfonatocalix[4]arenes and the antipsychotic drug chlorpromazine..” Soft Matter, vol. 10, no. 13, Dec. 2013, pp. 2253-2263. https://doi.org/10.1039/C3SM52866A.
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