volume 6 issue 7 pages 1285-1292

Substituted 4-hydroxy-1,2,3-triazoles: synthesis, characterization and first drug design applications through bioisosteric modulation and scaffold hopping approaches

Agnese C. Pippione 1
Franco Dosio 1
Alex Ducime 1
Antonella Federico 1
K. Martina 1
Stefano Sainas 1
Bente Frølund 2
Major Gooyit 3
Kim D. Janda 3
Donatella Boschi 1
Marco Lolli 1
Publication typeJournal Article
Publication date2015-05-28
SJR
CiteScore
Impact factor
ISSN20402503, 20402511
Organic Chemistry
Drug Discovery
Biochemistry
Pharmacology
Pharmaceutical Science
Molecular Medicine
Abstract

The hydroxytriazole system is here analysed and used to modulate acidic moieties present in lead compounds.

Found 
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GOST |
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GOST Copy
Pippione A. C. et al. Substituted 4-hydroxy-1,2,3-triazoles: synthesis, characterization and first drug design applications through bioisosteric modulation and scaffold hopping approaches // MedChemComm. 2015. Vol. 6. No. 7. pp. 1285-1292.
GOST all authors (up to 50) Copy
Pippione A. C., Dosio F., Ducime A., Federico A., Martina K., Sainas S., Frølund B., Gooyit M., Janda K. D., Boschi D., Lolli M. Substituted 4-hydroxy-1,2,3-triazoles: synthesis, characterization and first drug design applications through bioisosteric modulation and scaffold hopping approaches // MedChemComm. 2015. Vol. 6. No. 7. pp. 1285-1292.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1039/c5md00182j
UR - https://doi.org/10.1039/c5md00182j
TI - Substituted 4-hydroxy-1,2,3-triazoles: synthesis, characterization and first drug design applications through bioisosteric modulation and scaffold hopping approaches
T2 - MedChemComm
AU - Pippione, Agnese C.
AU - Dosio, Franco
AU - Ducime, Alex
AU - Federico, Antonella
AU - Martina, K.
AU - Sainas, Stefano
AU - Frølund, Bente
AU - Gooyit, Major
AU - Janda, Kim D.
AU - Boschi, Donatella
AU - Lolli, Marco
PY - 2015
DA - 2015/05/28
PB - Royal Society of Chemistry (RSC)
SP - 1285-1292
IS - 7
VL - 6
SN - 2040-2503
SN - 2040-2511
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2015_Pippione,
author = {Agnese C. Pippione and Franco Dosio and Alex Ducime and Antonella Federico and K. Martina and Stefano Sainas and Bente Frølund and Major Gooyit and Kim D. Janda and Donatella Boschi and Marco Lolli},
title = {Substituted 4-hydroxy-1,2,3-triazoles: synthesis, characterization and first drug design applications through bioisosteric modulation and scaffold hopping approaches},
journal = {MedChemComm},
year = {2015},
volume = {6},
publisher = {Royal Society of Chemistry (RSC)},
month = {may},
url = {https://doi.org/10.1039/c5md00182j},
number = {7},
pages = {1285--1292},
doi = {10.1039/c5md00182j}
}
MLA
Cite this
MLA Copy
Pippione, Agnese C., et al. “Substituted 4-hydroxy-1,2,3-triazoles: synthesis, characterization and first drug design applications through bioisosteric modulation and scaffold hopping approaches.” MedChemComm, vol. 6, no. 7, May. 2015, pp. 1285-1292. https://doi.org/10.1039/c5md00182j.