Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate
Polina Yaseneva
1
,
Paul Hodgson
1
,
Jacek Zakrzewski
1
,
Sebastian Falß
2
,
Rebecca E Meadows
3
,
Alexei Lapkin
1
1
2
INVITE GmbH, Chempark Leverkusen, 51373 Leverkusen, Germany
|
Publication type: Journal Article
Publication date: 2016-01-01
scimago Q2
wos Q2
SJR: 0.685
CiteScore: 5.6
Impact factor: 3.1
ISSN: 20589883
Catalysis
Chemistry (miscellaneous)
Process Chemistry and Technology
Chemical Engineering (miscellaneous)
Fluid Flow and Transfer Processes
Abstract
A flow process for direct amination of a pharmaceutically relevant substrate using a Pd-NHC based catalyst was demonstrated in a lab-scale mini-plant and in a pilot-scale plant.
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Metrics
47
Total citations:
47
Citations from 2024:
12
(25%)
Cite this
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RIS |
BibTex |
MLA
Cite this
GOST
Copy
Yaseneva P. et al. Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate // Reaction Chemistry and Engineering. 2016. Vol. 1. No. 2. pp. 229-238.
GOST all authors (up to 50)
Copy
Yaseneva P., Hodgson P., Zakrzewski J., Falß S., Meadows R. E., Lapkin A. Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate // Reaction Chemistry and Engineering. 2016. Vol. 1. No. 2. pp. 229-238.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1039/c5re00048c
UR - https://doi.org/10.1039/c5re00048c
TI - Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate
T2 - Reaction Chemistry and Engineering
AU - Yaseneva, Polina
AU - Hodgson, Paul
AU - Zakrzewski, Jacek
AU - Falß, Sebastian
AU - Meadows, Rebecca E
AU - Lapkin, Alexei
PY - 2016
DA - 2016/01/01
PB - Royal Society of Chemistry (RSC)
SP - 229-238
IS - 2
VL - 1
SN - 2058-9883
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2016_Yaseneva,
author = {Polina Yaseneva and Paul Hodgson and Jacek Zakrzewski and Sebastian Falß and Rebecca E Meadows and Alexei Lapkin},
title = {Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate},
journal = {Reaction Chemistry and Engineering},
year = {2016},
volume = {1},
publisher = {Royal Society of Chemistry (RSC)},
month = {jan},
url = {https://doi.org/10.1039/c5re00048c},
number = {2},
pages = {229--238},
doi = {10.1039/c5re00048c}
}
Cite this
MLA
Copy
Yaseneva, Polina, et al. “Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate.” Reaction Chemistry and Engineering, vol. 1, no. 2, Jan. 2016, pp. 229-238. https://doi.org/10.1039/c5re00048c.