volume 17 issue 4 pages 958-965

Synthesis of cyano-substituted carbazoles via successive C–C/C–H cleavage

Yajie Yang 1, 2, 3, 4, 5
Jiaqi Huang 1, 2, 3, 4, 5
Hailu Tan 1, 2, 3, 4, 5
Lingkai Kong 1, 2, 3, 4, 5
Mengdan Wang 1
Yang Yuan 1
Yanzhong Li 1, 2, 3, 4, 5
Publication typeJournal Article
Publication date2019-01-04
scimago Q2
wos Q2
SJR0.600
CiteScore5.2
Impact factor2.7
ISSN14770520, 14770539
PubMed ID:  30631868
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A highly efficient protocol for the synthesis of polysubstituted cyano carbazoles has been developed. This process is realized through the tandem reactions of Cs2CO3 promoted C–C σ-bond activation of α-cyano ketones followed by Fe-catalyzed selective C–H and/or C–C bond activations. Two of the sp2 C–H bonds are functionalized, and two of the C–C σ-bonds are cleaved involving a 1,2-acyl migration during the reaction process.
Found 
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GOST |
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GOST Copy
Yang Y. et al. Synthesis of cyano-substituted carbazoles via successive C–C/C–H cleavage // Organic and Biomolecular Chemistry. 2019. Vol. 17. No. 4. pp. 958-965.
GOST all authors (up to 50) Copy
Yang Y., Huang J., Tan H., Kong L., Wang M., Yuan Y., Li Y. Synthesis of cyano-substituted carbazoles via successive C–C/C–H cleavage // Organic and Biomolecular Chemistry. 2019. Vol. 17. No. 4. pp. 958-965.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1039/c8ob03031f
UR - https://xlink.rsc.org/?DOI=C8OB03031F
TI - Synthesis of cyano-substituted carbazoles via successive C–C/C–H cleavage
T2 - Organic and Biomolecular Chemistry
AU - Yang, Yajie
AU - Huang, Jiaqi
AU - Tan, Hailu
AU - Kong, Lingkai
AU - Wang, Mengdan
AU - Yuan, Yang
AU - Li, Yanzhong
PY - 2019
DA - 2019/01/04
PB - Royal Society of Chemistry (RSC)
SP - 958-965
IS - 4
VL - 17
PMID - 30631868
SN - 1477-0520
SN - 1477-0539
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2019_Yang,
author = {Yajie Yang and Jiaqi Huang and Hailu Tan and Lingkai Kong and Mengdan Wang and Yang Yuan and Yanzhong Li},
title = {Synthesis of cyano-substituted carbazoles via successive C–C/C–H cleavage},
journal = {Organic and Biomolecular Chemistry},
year = {2019},
volume = {17},
publisher = {Royal Society of Chemistry (RSC)},
month = {jan},
url = {https://xlink.rsc.org/?DOI=C8OB03031F},
number = {4},
pages = {958--965},
doi = {10.1039/c8ob03031f}
}
MLA
Cite this
MLA Copy
Yang, Yajie, et al. “Synthesis of cyano-substituted carbazoles via successive C–C/C–H cleavage.” Organic and Biomolecular Chemistry, vol. 17, no. 4, Jan. 2019, pp. 958-965. https://xlink.rsc.org/?DOI=C8OB03031F.