Open Access
Open access
Royal Society of Chemistry (RSC)
RSC Advances
,  volume 8 ,  issue 64 ,  pages 36980-36986

A nitroalkane-based approach to one-pot three-component synthesis of isocryptolepine and its analogs with potent anti-cancer activities

Nicolai A. Aksenov 1
, 
Alexander V. Aksenov 1
, 
Alexander Kornienko 2
, 
Annelise De Carvalho 3, 4
, 
VÉRONIQUE MATHIEU 3, 4
, 
Dmitrii A Aksenov 1
, 
Sergei N Ovcharov 1
, 
Georgii D Griaznov 5
, 
Michael Rubin 1, 5
1
 
2
 
3
 
4
 
5
 
Publication type: Journal Article
Publication date: 2018-11-01
Royal Society of Chemistry (RSC)
scimago Q1
wos Q2
SJR: 0.777
CiteScore: 7.6
Impact factor: 4.6
ISSN: 20462069
DOI:  10.1039/c8ra08155g
PubMed ID:  35558925
General Chemistry
General Chemical Engineering
Abstract

An improved one-pot three-component synthesis involving electrophilically activated nitroalkanes allowed for efficient preparation of indoloquinolines with potent anticancer activities.

Found 
Found 
11 citations
Aksenov Aleksandr
🥼 🤝
DSc in Chemistry, professor
243 publications,  2 187 citations,  15 reviews
h-index: 24
North Caucasus Federal University
North Caucasus Federal University
Research interests
Medicinal Chemistry
Organic Chemistry
3 citations
Arutiunov Nikolai
PhD in Chemistry, senior lecturer
28 publications,  232 citations
h-index: 9
North Caucasus Federal University
North Caucasus Federal University
2 citations
Beloglazkina Elena
DSc in Chemistry, professor
296 publications,  3 248 citations,  11 reviews
h-index: 29
Lomonosov Moscow State University
Lomonosov Moscow State University
2 citations
Sosnovskikh Vyacheslav
DSc in Chemistry, professor
355 publications,  4 721 citations
h-index: 30
Ural Federal University
Ural Federal University
1 citation
Karasik Andrey
DSc in Chemistry, professor, associate member of the Russian Academy of Sciences 
224 publications,  2 599 citations
h-index: 26
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
Research interests
Coordination Chemistry
Luminescence
Phosphorus ligands
1 citation
Zagidullin Almaz
🥼 🤝
PhD in Chemistry
81 publications,  884 citations
h-index: 17
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
Research interests
Asymmetric metal complex catalysis
Chemistry of organic and organoelement compounds; chemistry of polymers; production of materials
Coordination chemistry of phosphorus
Organoelement chemistry
Organophosphorus chemistry
Synthesis of chiral phosphorus-containing ligands
1 citation
Nesterov Nikolay
PhD in Chemistry
20 publications,  349 citations,  1 review
h-index: 10
Boreskov Institute of Catalysis of the Siberian Branch of the Russian Academy of Sciences
Boreskov Institute of Catalysis of the Siberian Branch of the Russian Academy of Sciences
1 citation
Ilkin Vladimir
PhD in Chemistry
16 publications,  187 citations
h-index: 7
Ural Federal University
Ural Federal University
Research interests
Catalysis
Heterocyclic compounds
Organic Chemistry
Synthetic Organic Chemistry
1 citation
Gafurov Zufar
🤝
PhD in Chemistry
47 publications,  634 citations
h-index: 17
Kazan Federal University
Kazan Federal University
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
Research interests
Catalysis
Coordination Chemistry
Electrochemistry
Organometallic Chemistry
1 citation
Ivleva Elena
67 publications,  469 citations
h-index: 12
Samara State Technical University
Samara State Technical University
Research interests
Organic Chemistry
Organic synthesis
1 citation
Kurenkov Igor
12 publications,  84 citations
h-index: 7
North Caucasus Federal University
North Caucasus Federal University
Research interests
Heterocyclic compounds
Organic Chemistry
Synthesis
1 citation
MALYUGA VLADIMIR
7 publications,  47 citations
h-index: 5
North Caucasus Federal University
North Caucasus Federal University
1 citation
Krylov Igor
PhD in Chemistry
78 publications,  1 885 citations,  18 reviews
h-index: 25
N.D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences
N.D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences
Research interests
Green chemistry
Organic Chemistry
Organic electrochemistry
Organic synthesis
Photochemistry
Plant protection
1 citation
Kantyukov Artyom
32 publications,  420 citations
h-index: 11
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
A.E. Arbuzov Institute of Organic and Physical Chemistry of the Kazan Scientific Center of the Russian Academy of Sciences
Kazan Federal University
Kazan Federal University
1 citation
Varaksin Mikhail
DSc in Chemistry
77 publications,  807 citations,  12 reviews
h-index: 18
Postovsky Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Sciences
Postovsky Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Sciences
Ural Federal University
Ural Federal University
1 citation
Tikhomirov Alexander
🥼 🤝
DSc in Chemistry, associate professor
59 publications,  920 citations
h-index: 17
Mendeleev University of Chemical Technology of Russia
Mendeleev University of Chemical Technology of Russia
Gause Institute of New Antibiotics
Gause Institute of New Antibiotics
Research interests
Medicinal Chemistry
1 citation
Akulov Alexey
PhD in Chemistry
16 publications,  171 citations
h-index: 7
Ural Federal University
Ural Federal University
Research interests
C-H functionalization
Chemistry of heterocycles
Organic Chemistry
Photochemistry
1 citation
Ivanov Andrey
54 publications,  534 citations
h-index: 12
A.E. Favorsky Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences
A.E. Favorsky Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences
1 citation
Buev Evgeny
PhD in Chemistry
31 publications,  346 citations,  2 reviews
h-index: 9
Ural Federal University
Ural Federal University
Research interests
Chemistry of nitrogen-containing heterocycles
Organic Chemistry
Organic synthesis

Top-30

Journals

1
2
Russian Chemical Bulletin
Russian Chemical Bulletin, 2, 7.41%
Russian Chemical Bulletin
2 publications, 7.41%
ChemMedChem
ChemMedChem, 2, 7.41%
ChemMedChem
2 publications, 7.41%
Russian Chemical Reviews
Russian Chemical Reviews, 2, 7.41%
Russian Chemical Reviews
2 publications, 7.41%
Journal of Agricultural and Food Chemistry
Journal of Agricultural and Food Chemistry, 2, 7.41%
Journal of Agricultural and Food Chemistry
2 publications, 7.41%
Chemical and Pharmaceutical Bulletin
Chemical and Pharmaceutical Bulletin, 1, 3.7%
Chemical and Pharmaceutical Bulletin
1 publication, 3.7%
Chemistry of Heterocyclic Compounds
Chemistry of Heterocyclic Compounds, 1, 3.7%
Chemistry of Heterocyclic Compounds
1 publication, 3.7%
Molecules
Molecules, 1, 3.7%
Molecules
1 publication, 3.7%
Tetrahedron Letters
Tetrahedron Letters, 1, 3.7%
Tetrahedron Letters
1 publication, 3.7%
Applied Organometallic Chemistry
Applied Organometallic Chemistry, 1, 3.7%
Applied Organometallic Chemistry
1 publication, 3.7%
Chemistry - An Asian Journal
Chemistry - An Asian Journal, 1, 3.7%
Chemistry - An Asian Journal
1 publication, 3.7%
Journal of Organic Chemistry
Journal of Organic Chemistry, 1, 3.7%
Journal of Organic Chemistry
1 publication, 3.7%
Organic Letters
Organic Letters, 1, 3.7%
Organic Letters
1 publication, 3.7%
Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, 1, 3.7%
Organic and Biomolecular Chemistry
1 publication, 3.7%
RSC Advances
RSC Advances, 1, 3.7%
RSC Advances
1 publication, 3.7%
Heterocycles
Heterocycles, 1, 3.7%
Heterocycles
1 publication, 3.7%
Asian Journal of Organic Chemistry
Asian Journal of Organic Chemistry, 1, 3.7%
Asian Journal of Organic Chemistry
1 publication, 3.7%
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, 1, 3.7%
International Journal for Parasitology: Drugs and Drug Resistance
1 publication, 3.7%
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 1, 3.7%
International Journal of Molecular Sciences
1 publication, 3.7%
Bioorganic Chemistry
Bioorganic Chemistry, 1, 3.7%
Bioorganic Chemistry
1 publication, 3.7%
Russian Journal of Organic Chemistry
Russian Journal of Organic Chemistry, 1, 3.7%
Russian Journal of Organic Chemistry
1 publication, 3.7%
Журнал органической химии
Журнал органической химии, 1, 3.7%
Журнал органической химии
1 publication, 3.7%
MolBank
MolBank, 1, 3.7%
MolBank
1 publication, 3.7%
Tetrahedron
Tetrahedron, 1, 3.7%
Tetrahedron
1 publication, 3.7%
1
2

Publishers

1
2
3
4
5
Wiley
Wiley, 5, 18.52%
Wiley
5 publications, 18.52%
Elsevier
Elsevier, 4, 14.81%
Elsevier
4 publications, 14.81%
American Chemical Society (ACS)
American Chemical Society (ACS), 4, 14.81%
American Chemical Society (ACS)
4 publications, 14.81%
Springer Nature
Springer Nature, 3, 11.11%
Springer Nature
3 publications, 11.11%
MDPI
MDPI, 3, 11.11%
MDPI
3 publications, 11.11%
Royal Society of Chemistry (RSC)
Royal Society of Chemistry (RSC), 2, 7.41%
Royal Society of Chemistry (RSC)
2 publications, 7.41%
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii, 2, 7.41%
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
2 publications, 7.41%
Pharmaceutical Society of Japan
Pharmaceutical Society of Japan, 1, 3.7%
Pharmaceutical Society of Japan
1 publication, 3.7%
The Japan Institute of Heterocyclic Chemistry
The Japan Institute of Heterocyclic Chemistry, 1, 3.7%
The Japan Institute of Heterocyclic Chemistry
1 publication, 3.7%
Pleiades Publishing
Pleiades Publishing, 1, 3.7%
Pleiades Publishing
1 publication, 3.7%
The Russian Academy of Sciences
The Russian Academy of Sciences, 1, 3.7%
The Russian Academy of Sciences
1 publication, 3.7%
1
2
3
4
5
  • We do not take into account publications without a DOI.
  • Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
27
Share
Cite this
GOST |
Cite this
GOST Copy
Aksenov N. A. et al. A nitroalkane-based approach to one-pot three-component synthesis of isocryptolepine and its analogs with potent anti-cancer activities // RSC Advances. 2018. Vol. 8. No. 64. pp. 36980-36986.
GOST all authors (up to 50) Copy
Aksenov N. A., Aksenov A., Kornienko A., De Carvalho A., MATHIEU V., Aksenov D. A., Ovcharov S. N., Griaznov G. D., Rubin M. A nitroalkane-based approach to one-pot three-component synthesis of isocryptolepine and its analogs with potent anti-cancer activities // RSC Advances. 2018. Vol. 8. No. 64. pp. 36980-36986.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1039/c8ra08155g
UR - https://doi.org/10.1039/c8ra08155g
TI - A nitroalkane-based approach to one-pot three-component synthesis of isocryptolepine and its analogs with potent anti-cancer activities
T2 - RSC Advances
AU - Aksenov, Nicolai A.
AU - Aksenov, Alexander V.
AU - Kornienko, Alexander
AU - De Carvalho, Annelise
AU - MATHIEU, VÉRONIQUE
AU - Aksenov, Dmitrii A
AU - Ovcharov, Sergei N
AU - Griaznov, Georgii D
AU - Rubin, Michael
PY - 2018
DA - 2018/11/01
PB - Royal Society of Chemistry (RSC)
SP - 36980-36986
IS - 64
VL - 8
PMID - 35558925
SN - 2046-2069
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2018_Aksenov,
author = {Nicolai A. Aksenov and Alexander V. Aksenov and Alexander Kornienko and Annelise De Carvalho and VÉRONIQUE MATHIEU and Dmitrii A Aksenov and Sergei N Ovcharov and Georgii D Griaznov and Michael Rubin},
title = {A nitroalkane-based approach to one-pot three-component synthesis of isocryptolepine and its analogs with potent anti-cancer activities},
journal = {RSC Advances},
year = {2018},
volume = {8},
publisher = {Royal Society of Chemistry (RSC)},
month = {nov},
url = {https://doi.org/10.1039/c8ra08155g},
number = {64},
pages = {36980--36986},
doi = {10.1039/c8ra08155g}
}
MLA
Cite this
MLA Copy
Aksenov, Nicolai A., et al. “A nitroalkane-based approach to one-pot three-component synthesis of isocryptolepine and its analogs with potent anti-cancer activities.” RSC Advances, vol. 8, no. 64, Nov. 2018, pp. 36980-36986. https://doi.org/10.1039/c8ra08155g.