volume 21 issue 23 pages 6353-6360

Diastereoselective synthesis of CF3-oxazinoquinolines in water

Publication typeJournal Article
Publication date2019-10-16
scimago Q1
wos Q1
SJR1.928
CiteScore16.1
Impact factor9.2
ISSN14639262, 14639270
Environmental Chemistry
Pollution
Abstract
A highly efficient stereoselective synthesis of CF3-oxazinoquinolines was elaborated using the reaction of CF3-ynones with quinolines in water. It was demonstrated that under these green conditions, the reaction proceeds up to 20 times faster to provide target compounds in almost quantitative yields. Moreover, this method is devoid of any chromatographic purification to give CF3-oxazinoquinolines with complete diastereoselectivity. The presented eco-friendly approach was found much more efficient than standard reactions in organic solvents. The synthetic utility of the prepared CF3-oxazinoquinolines was demonstrated.
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GOST |
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GOST Copy
Muzalevskiy V. M. et al. Diastereoselective synthesis of CF3-oxazinoquinolines in water // Green Chemistry. 2019. Vol. 21. No. 23. pp. 6353-6360.
GOST all authors (up to 50) Copy
Muzalevskiy V. M., Belyaeva K. V., Trofimov B. A., Nenajdenko V. G. Diastereoselective synthesis of CF3-oxazinoquinolines in water // Green Chemistry. 2019. Vol. 21. No. 23. pp. 6353-6360.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1039/c9gc03044a
UR - https://xlink.rsc.org/?DOI=C9GC03044A
TI - Diastereoselective synthesis of CF3-oxazinoquinolines in water
T2 - Green Chemistry
AU - Muzalevskiy, Vasily M.
AU - Belyaeva, Kseniya V
AU - Trofimov, B. A.
AU - Nenajdenko, Valentine G.
PY - 2019
DA - 2019/10/16
PB - Royal Society of Chemistry (RSC)
SP - 6353-6360
IS - 23
VL - 21
SN - 1463-9262
SN - 1463-9270
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2019_Muzalevskiy,
author = {Vasily M. Muzalevskiy and Kseniya V Belyaeva and B. A. Trofimov and Valentine G. Nenajdenko},
title = {Diastereoselective synthesis of CF3-oxazinoquinolines in water},
journal = {Green Chemistry},
year = {2019},
volume = {21},
publisher = {Royal Society of Chemistry (RSC)},
month = {oct},
url = {https://xlink.rsc.org/?DOI=C9GC03044A},
number = {23},
pages = {6353--6360},
doi = {10.1039/c9gc03044a}
}
MLA
Cite this
MLA Copy
Muzalevskiy, Vasily M., et al. “Diastereoselective synthesis of CF3-oxazinoquinolines in water.” Green Chemistry, vol. 21, no. 23, Oct. 2019, pp. 6353-6360. https://xlink.rsc.org/?DOI=C9GC03044A.