Consecutive multicomponent reactions for the synthesis of complex molecules.
2
Jiangsu Key Laboratory for the Chemistry of Low-dimensional Materials
4
Jiangsu 223300
5
CHINA
|
6
7
School of Pharmaceutical Engineering and Life Science
9
Jiangsu 213164
12
Boston
13
Usa
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Publication type: Journal Article
Publication date: 2019-07-15
scimago Q2
wos Q2
SJR: 0.600
CiteScore: 5.2
Impact factor: 2.7
ISSN: 14770520, 14770539
PubMed ID:
31339143
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
Multicomponent reactions (MCRs) involving a minimum of three reactants or reaction centers are conducted in one pot and with a single operational step. This synthetic method has a good pot, atom and step economy in the preparation of diverse and complex molecular scaffolds. Consecutive MCRs, also known as sequential or multiple MCRs, by combining two or more MCRs, exhibit even higher synthetic efficiency, product structural diversity, and molecular complexity. This review article highlights the Ugi, Groebke-Blackburn-Bienaymé, Biginelli, Huisgen, Petasis, Gewald, and Asinger reaction-initiated consecutive MCRs.
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262
Total citations:
262
Citations from 2025:
39
(14.88%)
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Zhi S. et al. Consecutive multicomponent reactions for the synthesis of complex molecules. // Organic and Biomolecular Chemistry. 2019. Vol. 17. No. 33. pp. 7632-7650.
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Zhi S., Ma X., Zhang W. Consecutive multicomponent reactions for the synthesis of complex molecules. // Organic and Biomolecular Chemistry. 2019. Vol. 17. No. 33. pp. 7632-7650.
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TY - JOUR
DO - 10.1039/C9OB00772E
UR - https://xlink.rsc.org/?DOI=C9OB00772E
TI - Consecutive multicomponent reactions for the synthesis of complex molecules.
T2 - Organic and Biomolecular Chemistry
AU - Zhi, Sanjun
AU - Ma, Xiaoming
AU - Zhang, Wei
PY - 2019
DA - 2019/07/15
PB - Royal Society of Chemistry (RSC)
SP - 7632-7650
IS - 33
VL - 17
PMID - 31339143
SN - 1477-0520
SN - 1477-0539
ER -
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BibTex (up to 50 authors)
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@article{2019_Zhi,
author = {Sanjun Zhi and Xiaoming Ma and Wei Zhang},
title = {Consecutive multicomponent reactions for the synthesis of complex molecules.},
journal = {Organic and Biomolecular Chemistry},
year = {2019},
volume = {17},
publisher = {Royal Society of Chemistry (RSC)},
month = {jul},
url = {https://xlink.rsc.org/?DOI=C9OB00772E},
number = {33},
pages = {7632--7650},
doi = {10.1039/C9OB00772E}
}
Cite this
MLA
Copy
Zhi, Sanjun, et al. “Consecutive multicomponent reactions for the synthesis of complex molecules..” Organic and Biomolecular Chemistry, vol. 17, no. 33, Jul. 2019, pp. 7632-7650. https://xlink.rsc.org/?DOI=C9OB00772E.