Chemical Communications, volume 57, issue 85, pages 11201-11204

Construction of an isoquinolinone framework from carboxylic-ester-directed umpolung ring opening of methylenecyclopropanes

Publication typeJournal Article
Publication date2021-09-27
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor4.9
ISSN13597345, 1364548X
Materials Chemistry
Metals and Alloys
Surfaces, Coatings and Films
General Chemistry
Ceramics and Composites
Electronic, Optical and Magnetic Materials
Catalysis
Abstract
An interesting type of reaction involving functionalized methylenecyclopropanes (MCPs) has been revealed. Here, a nucleophilic attack of an anionic species onto a partially polarity-reversed MCP was realized by treating a neighbouring carboxylic ester tethered to the MCP and amine with KHMDS to realize an umpolung ring opening of the MCP. This work established an operationally convenient protocol for the rapid construction of isoquinolinone frameworks.

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GOST |
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GOST Copy
Wei H. Z. et al. Construction of an isoquinolinone framework from carboxylic-ester-directed umpolung ring opening of methylenecyclopropanes // Chemical Communications. 2021. Vol. 57. No. 85. pp. 11201-11204.
GOST all authors (up to 50) Copy
Wei H. Z., Wei H., Wei Yin 尹., Shi M. Construction of an isoquinolinone framework from carboxylic-ester-directed umpolung ring opening of methylenecyclopropanes // Chemical Communications. 2021. Vol. 57. No. 85. pp. 11201-11204.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1039/d1cc04826k
UR - https://doi.org/10.1039/d1cc04826k
TI - Construction of an isoquinolinone framework from carboxylic-ester-directed umpolung ring opening of methylenecyclopropanes
T2 - Chemical Communications
AU - Wei, Hao Zhao
AU - Shi, Min
AU - Wei Yin, 尹维
AU - Wei, Hao-Zhao
PY - 2021
DA - 2021/09/27 00:00:00
PB - Royal Society of Chemistry (RSC)
SP - 11201-11204
IS - 85
VL - 57
SN - 1359-7345
SN - 1364-548X
ER -
BibTex |
Cite this
BibTex Copy
@article{2021_Wei,
author = {Hao Zhao Wei and Min Shi and 尹维 Wei Yin and Hao-Zhao Wei},
title = {Construction of an isoquinolinone framework from carboxylic-ester-directed umpolung ring opening of methylenecyclopropanes},
journal = {Chemical Communications},
year = {2021},
volume = {57},
publisher = {Royal Society of Chemistry (RSC)},
month = {sep},
url = {https://doi.org/10.1039/d1cc04826k},
number = {85},
pages = {11201--11204},
doi = {10.1039/d1cc04826k}
}
MLA
Cite this
MLA Copy
Wei, Hao Zhao, et al. “Construction of an isoquinolinone framework from carboxylic-ester-directed umpolung ring opening of methylenecyclopropanes.” Chemical Communications, vol. 57, no. 85, Sep. 2021, pp. 11201-11204. https://doi.org/10.1039/d1cc04826k.
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