Open Access
Organocatalyzed [4 + 2] cycloaddition of α,β-unsaturated ketones and isatylidene malononitrile: accessing spiro[3-arylcyclohexanone]oxindole derivatives
Baliram R. Patil
1, 2
,
Chandrakant B. Nichinde
1, 2
,
Suryakant S. Chaudhari
1, 2
,
Gamidi Rama Krishna
3
,
A.K Kinage
1, 2
2
Academy of Scientific and innovative Research (AcSIR), Ghaziabad 201002, India
|
Publication type: Journal Article
Publication date: 2024-01-17
scimago Q1
wos Q2
SJR: 0.777
CiteScore: 7.6
Impact factor: 4.6
ISSN: 20462069
PubMed ID:
38239455
General Chemistry
General Chemical Engineering
Abstract
Herein, we developed a series of compounds featuring spiro[3-arylcyclohexanone]oxindoles through Barbas [4 + 2] cycloaddition reactions between isatylidene malononitrile and α,β-unsaturated ketones using L-proline as an organocatalyst. The reported methodology offers many advantages such as mild reaction conditions, diverse substrate scope with high yields, easy reaction setup, and use of easily synthesizable starting materials.
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6
Total citations:
6
Citations from 2024:
6
(100%)
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Patil B. R. et al. Organocatalyzed [4 + 2] cycloaddition of α,β-unsaturated ketones and isatylidene malononitrile: accessing spiro[3-arylcyclohexanone]oxindole derivatives // RSC Advances. 2024. Vol. 14. No. 5. pp. 2873-2877.
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Patil B. R., Nichinde C. B., Chaudhari S. S., Krishna G. R., Kinage A. Organocatalyzed [4 + 2] cycloaddition of α,β-unsaturated ketones and isatylidene malononitrile: accessing spiro[3-arylcyclohexanone]oxindole derivatives // RSC Advances. 2024. Vol. 14. No. 5. pp. 2873-2877.
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RIS
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TY - JOUR
DO - 10.1039/d3ra07652k
UR - https://xlink.rsc.org/?DOI=D3RA07652K
TI - Organocatalyzed [4 + 2] cycloaddition of α,β-unsaturated ketones and isatylidene malononitrile: accessing spiro[3-arylcyclohexanone]oxindole derivatives
T2 - RSC Advances
AU - Patil, Baliram R.
AU - Nichinde, Chandrakant B.
AU - Chaudhari, Suryakant S.
AU - Krishna, Gamidi Rama
AU - Kinage, A.K
PY - 2024
DA - 2024/01/17
PB - Royal Society of Chemistry (RSC)
SP - 2873-2877
IS - 5
VL - 14
PMID - 38239455
SN - 2046-2069
ER -
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BibTex (up to 50 authors)
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@article{2024_Patil,
author = {Baliram R. Patil and Chandrakant B. Nichinde and Suryakant S. Chaudhari and Gamidi Rama Krishna and A.K Kinage},
title = {Organocatalyzed [4 + 2] cycloaddition of α,β-unsaturated ketones and isatylidene malononitrile: accessing spiro[3-arylcyclohexanone]oxindole derivatives},
journal = {RSC Advances},
year = {2024},
volume = {14},
publisher = {Royal Society of Chemistry (RSC)},
month = {jan},
url = {https://xlink.rsc.org/?DOI=D3RA07652K},
number = {5},
pages = {2873--2877},
doi = {10.1039/d3ra07652k}
}
Cite this
MLA
Copy
Patil, Baliram R., et al. “Organocatalyzed [4 + 2] cycloaddition of α,β-unsaturated ketones and isatylidene malononitrile: accessing spiro[3-arylcyclohexanone]oxindole derivatives.” RSC Advances, vol. 14, no. 5, Jan. 2024, pp. 2873-2877. https://xlink.rsc.org/?DOI=D3RA07652K.