Chemical Communications

, том 49 , издание 62 , страницы 6959

Solid phase click ligation for the synthesis of very long oligonucleotides.

Тип публикации: Journal Article

Дата публикации: 2013-06-21

Royal Society of Chemistry (RSC)

Chemical Communications

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SJR: 0.907

CiteScore: 7.2

Impact factor: 4.3

ISSN: 13597345, 1364548X

DOI: 10.1039/c3cc42451k

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PubMed ID: 23814786

Materials Chemistry

Metals and Alloys

Surfaces, Coatings and Films

General Chemistry

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Electronic, Optical and Magnetic Materials

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Краткое описание

Oligonucleotides have been ligated efficiently on solid-phase using CuAAC and SPAAC chemistry to produce up to 186-mer triazole linked DNA products. Multiple sequential ligation reactions can be carried out by using a masked azide approach. This work suggests a novel modular approach to the synthesis of large complex oligonucleotide analogues.

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Qiu J. et al. Solid phase click ligation for the synthesis of very long oligonucleotides. // Chemical Communications. 2013. Vol. 49. No. 62. p. 6959.

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Qiu J., El-Sagheer A. H., Brown T. Solid phase click ligation for the synthesis of very long oligonucleotides. // Chemical Communications. 2013. Vol. 49. No. 62. p. 6959.

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TY - JOUR

DO - 10.1039/c3cc42451k

UR - https://doi.org/10.1039/c3cc42451k

TI - Solid phase click ligation for the synthesis of very long oligonucleotides.

T2 - Chemical Communications

AU - Qiu, Jieqiong

AU - El-Sagheer, Afaf H.

AU - Brown, Tom

PY - 2013

DA - 2013/06/21

PB - Royal Society of Chemistry (RSC)

SP - 6959

IS - 62

VL - 49

PMID - 23814786

SN - 1359-7345

SN - 1364-548X

ER -

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@article{2013_Qiu,

author = {Jieqiong Qiu and Afaf H. El-Sagheer and Tom Brown},

title = {Solid phase click ligation for the synthesis of very long oligonucleotides.},

journal = {Chemical Communications},

year = {2013},

volume = {49},

publisher = {Royal Society of Chemistry (RSC)},

month = {jun},

url = {https://doi.org/10.1039/c3cc42451k},

number = {62},

pages = {6959},

doi = {10.1039/c3cc42451k}

}

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Qiu, Jieqiong, et al. “Solid phase click ligation for the synthesis of very long oligonucleotides..” Chemical Communications, vol. 49, no. 62, Jun. 2013, p. 6959. https://doi.org/10.1039/c3cc42451k.

Издатель

Royal Society of Chemistry (RSC)

Журнал

Chemical Communications

SCImago Q1

WOS Q2

БС1