Hybrid photoactive fullerene derivative-ruboxyl nanostructures for photodynamic therapy
Alexander I Kotelnikov
1
,
Alexander Yu Rybkin
1
,
Ekaterina A Khakina
1
,
A. B. Kornev
1
,
Alexander V Barinov
1
,
Anastasiya V Ivanchikhina
1
,
A. S. Peregudov
2
,
V.M Martynenko
1
,
Publication type: Journal Article
Publication date: 2013-04-09
scimago Q2
wos Q2
SJR: 0.600
CiteScore: 5.2
Impact factor: 2.7
ISSN: 14770520, 14770539
PubMed ID:
23712714
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
Here we report the investigation of photophysical properties and photodynamic action of two novel water soluble hybrid molecular structures based on [60]fullerene dyads bearing covalently attached residues of anthracycline antibiotic "ruboxyl". Molecular structures of the designed compounds were confirmed by IR and UV-VIS absorption spectroscopy, electrospray mass spectrometry (compound 5), and (1)H and (13)C NMR spectroscopy. Dynamic light scattering, steady-state and kinetic fluorimetry and UV-VIS absorption spectroscopy techniques were used to study the behavior of the synthesized hybrid molecular structures in aqueous solutions. Photodynamic activity of the compounds was evaluated by monitoring the O2(-) generation under visible light irradiation using the NBT test. It has been shown that the anthracycline chromophore (ruboxyl moiety possesses no photodynamic activity) behaves as an efficient photosensitizer for the fullerene core operating via the energy and/or the electron transfer pathways. The presented approach opens up wide opportunities for the design of various fullerene-based donor-acceptor systems with enhanced photodynamic properties potentially suitable for biomedicinal applications.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
|
|
|
Dyes and Pigments
4 publications, 16%
|
|
|
Doklady Physical Chemistry
3 publications, 12%
|
|
|
Pharmaceutical Chemistry Journal
1 publication, 4%
|
|
|
Optics and Spectroscopy (English translation of Optika i Spektroskopiya)
1 publication, 4%
|
|
|
Biochimica et Biophysica Acta - Biomembranes
1 publication, 4%
|
|
|
Chemical Communications
1 publication, 4%
|
|
|
Cancer Nanotechnology
1 publication, 4%
|
|
|
Journal of Photochemistry and Photobiology A: Chemistry
1 publication, 4%
|
|
|
Biosensors and Bioelectronics
1 publication, 4%
|
|
|
Mendeleev Communications
1 publication, 4%
|
|
|
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
1 publication, 4%
|
|
|
Cytometry. Part A : the journal of the International Society for Analytical Cytology
1 publication, 4%
|
|
|
Angewandte Chemie
1 publication, 4%
|
|
|
Angewandte Chemie - International Edition
1 publication, 4%
|
|
|
Zeitschrift fur Anorganische und Allgemeine Chemie
1 publication, 4%
|
|
|
Biomacromolecules
1 publication, 4%
|
|
|
Advanced healthcare materials
1 publication, 4%
|
|
|
Macroheterocycles
1 publication, 4%
|
|
|
Nanobiotechnology Reports
1 publication, 4%
|
|
|
1
2
3
4
|
Publishers
|
1
2
3
4
5
6
7
8
9
|
|
|
Elsevier
9 publications, 36%
|
|
|
Pleiades Publishing
5 publications, 20%
|
|
|
Wiley
5 publications, 20%
|
|
|
Springer Nature
2 publications, 8%
|
|
|
Royal Society of Chemistry (RSC)
1 publication, 4%
|
|
|
OOO Zhurnal "Mendeleevskie Soobshcheniya"
1 publication, 4%
|
|
|
American Chemical Society (ACS)
1 publication, 4%
|
|
|
Ivanovo State University of Chemistry and Technology
1 publication, 4%
|
|
|
1
2
3
4
5
6
7
8
9
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
25
Total citations:
25
Citations from 2025:
0
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Kotelnikov A. I. et al. Hybrid photoactive fullerene derivative-ruboxyl nanostructures for photodynamic therapy // Organic and Biomolecular Chemistry. 2013. Vol. 11. No. 26. pp. 4397-4404.
GOST all authors (up to 50)
Copy
Kotelnikov A. I., Rybkin A. Yu., Khakina E. A., Kornev A. B., Barinov A. V., Goryachev N. A., Ivanchikhina A. V., Peregudov A. S., Martynenko V., Troshin P. A. Hybrid photoactive fullerene derivative-ruboxyl nanostructures for photodynamic therapy // Organic and Biomolecular Chemistry. 2013. Vol. 11. No. 26. pp. 4397-4404.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1039/c3ob40136g
UR - https://doi.org/10.1039/c3ob40136g
TI - Hybrid photoactive fullerene derivative-ruboxyl nanostructures for photodynamic therapy
T2 - Organic and Biomolecular Chemistry
AU - Kotelnikov, Alexander I
AU - Rybkin, Alexander Yu
AU - Khakina, Ekaterina A
AU - Kornev, A. B.
AU - Barinov, Alexander V
AU - Goryachev, Nikolay A.
AU - Ivanchikhina, Anastasiya V
AU - Peregudov, A. S.
AU - Martynenko, V.M
AU - Troshin, Pavel A.
PY - 2013
DA - 2013/04/09
PB - Royal Society of Chemistry (RSC)
SP - 4397-4404
IS - 26
VL - 11
PMID - 23712714
SN - 1477-0520
SN - 1477-0539
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2013_Kotelnikov,
author = {Alexander I Kotelnikov and Alexander Yu Rybkin and Ekaterina A Khakina and A. B. Kornev and Alexander V Barinov and Nikolay A. Goryachev and Anastasiya V Ivanchikhina and A. S. Peregudov and V.M Martynenko and Pavel A. Troshin},
title = {Hybrid photoactive fullerene derivative-ruboxyl nanostructures for photodynamic therapy},
journal = {Organic and Biomolecular Chemistry},
year = {2013},
volume = {11},
publisher = {Royal Society of Chemistry (RSC)},
month = {apr},
url = {https://doi.org/10.1039/c3ob40136g},
number = {26},
pages = {4397--4404},
doi = {10.1039/c3ob40136g}
}
Cite this
MLA
Copy
Kotelnikov, Alexander I., et al. “Hybrid photoactive fullerene derivative-ruboxyl nanostructures for photodynamic therapy.” Organic and Biomolecular Chemistry, vol. 11, no. 26, Apr. 2013, pp. 4397-4404. https://doi.org/10.1039/c3ob40136g.