Reversibility of the thia-Michael reaction of cytotoxic C5-curcuminoid and structure–activity relationship of bis-thiol-adducts thereof
Aki Kohyama
1
,
Michihiro Fukuda
1
,
Shunsuke Sugiyama
2
,
Hiroyuki Yamakoshi
1
,
Naoki Kanoh
1
,
Chikashi Ishioka
2
,
Hiroyuki Shibata
3
,
Yoshiharu Iwabuchi
1
Publication type: Journal Article
Publication date: 2016-10-24
scimago Q2
wos Q2
SJR: 0.600
CiteScore: 5.2
Impact factor: 2.7
ISSN: 14770520, 14770539
PubMed ID:
27801454
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A panel of GO-Y030-bis-thiol-adducts were synthesized and the structure–reactivity relationship regarding the retro thia-Michael reaction as well as the cell growth inhibitory activity against human colon cancer HCT116 were evaluated.
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Metrics
19
Total citations:
19
Citations from 2024:
3
(15.79%)
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MLA
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GOST
Copy
Kohyama A. et al. Reversibility of the thia-Michael reaction of cytotoxic C5-curcuminoid and structure–activity relationship of bis-thiol-adducts thereof // Organic and Biomolecular Chemistry. 2016. Vol. 14. No. 45. pp. 10683-10687.
GOST all authors (up to 50)
Copy
Kohyama A., Fukuda M., Sugiyama S., Yamakoshi H., Kanoh N., Ishioka C., Shibata H., Iwabuchi Y. Reversibility of the thia-Michael reaction of cytotoxic C5-curcuminoid and structure–activity relationship of bis-thiol-adducts thereof // Organic and Biomolecular Chemistry. 2016. Vol. 14. No. 45. pp. 10683-10687.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1039/c6ob01771a
UR - https://doi.org/10.1039/c6ob01771a
TI - Reversibility of the thia-Michael reaction of cytotoxic C5-curcuminoid and structure–activity relationship of bis-thiol-adducts thereof
T2 - Organic and Biomolecular Chemistry
AU - Kohyama, Aki
AU - Fukuda, Michihiro
AU - Sugiyama, Shunsuke
AU - Yamakoshi, Hiroyuki
AU - Kanoh, Naoki
AU - Ishioka, Chikashi
AU - Shibata, Hiroyuki
AU - Iwabuchi, Yoshiharu
PY - 2016
DA - 2016/10/24
PB - Royal Society of Chemistry (RSC)
SP - 10683-10687
IS - 45
VL - 14
PMID - 27801454
SN - 1477-0520
SN - 1477-0539
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2016_Kohyama,
author = {Aki Kohyama and Michihiro Fukuda and Shunsuke Sugiyama and Hiroyuki Yamakoshi and Naoki Kanoh and Chikashi Ishioka and Hiroyuki Shibata and Yoshiharu Iwabuchi},
title = {Reversibility of the thia-Michael reaction of cytotoxic C5-curcuminoid and structure–activity relationship of bis-thiol-adducts thereof},
journal = {Organic and Biomolecular Chemistry},
year = {2016},
volume = {14},
publisher = {Royal Society of Chemistry (RSC)},
month = {oct},
url = {https://doi.org/10.1039/c6ob01771a},
number = {45},
pages = {10683--10687},
doi = {10.1039/c6ob01771a}
}
Cite this
MLA
Copy
Kohyama, Aki, et al. “Reversibility of the thia-Michael reaction of cytotoxic C5-curcuminoid and structure–activity relationship of bis-thiol-adducts thereof.” Organic and Biomolecular Chemistry, vol. 14, no. 45, Oct. 2016, pp. 10683-10687. https://doi.org/10.1039/c6ob01771a.