Open Access
Open access
RSC Advances, volume 9, issue 1, pages 23-26

Tetra-fluorinated aromatic azide for highly efficient bioconjugation in living cells

Xuekang Cai 1, 2, 3, 4, 5
Dan Wang 6, 7, 8, 9, 10
Yasi Gao 4, 5, 11, 12
Long Yi 4, 5, 11, 12, 13
Xing Yang 1, 2, 3, 4, 14
Zhen Xi 6, 7, 8, 9, 10
1
 
Department of Nuclear Medicine
3
 
Beijing
4
 
CHINA
5
 
State Key Laboratory of Organic–Inorganic Composites
6
 
State Key Laboratory of Elemento-organic Chemistry
7
 
Department of Chemical Biology
8
 
National Pesticide Engineering Research Center (Tianjin)
10
 
Tianjin
12
 
Beijing 100029
Publication typeJournal Article
Publication date2019-01-01
Journal: RSC Advances
scimago Q1
SJR0.715
CiteScore7.5
Impact factor3.9
ISSN20462069
General Chemistry
General Chemical Engineering
Abstract

A fast strain-promoted azide–alkyne cycloaddition based on tetra-fluorinated aromatic azide was developed and applied to label proteins and living cells with high efficiency.

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