Spiropyrans for light-controlled drug delivery
Francesca Cardano
1, 2, 3, 4, 5, 6, 7
,
Elisa Del Canto
8, 9, 10, 11, 12, 13
,
Silvia Giordani
1, 3, 4, 5, 6, 14, 15
1
4
Nano Carbon Materials
5
10144 Turin
|
6
ITALY
|
10
School of chemistry
11
College Green
12
Dublin 2
13
Ireland
|
Publication type: Journal Article
Publication date: 2019-07-10
scimago Q2
wos Q1
SJR: 0.653
CiteScore: 6.0
Impact factor: 3.3
ISSN: 14779226, 14779234
PubMed ID:
31339137
Inorganic Chemistry
Abstract
The supramolecular assembly of acetylsalicylic acid to a merocyanine–Zn complex translates into a photo-controllable drug delivery system. Herein, we present the synthesis and spectroscopic analysis of a three-component assembly combining a spiropyran derivative, a zinc(II) cation, and acetylsalicylic acid. The ON/OFF system can be modulated by safe and easily affordable stimuli, for the specific delivery of more than one active compound. Our results confirm the formation of a ternary system in solution, where the behaviour is dominated by photo-induced responses, and pave the way for the use of such smart platforms for medicinal chemistry purposes.
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Metrics
40
Total citations:
40
Citations from 2025:
1
(2.5%)
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RIS |
BibTex |
MLA
Cite this
GOST
Copy
Cardano F. et al. Spiropyrans for light-controlled drug delivery // Dalton Transactions. 2019. Vol. 48. No. 41. pp. 15537-15544.
GOST all authors (up to 50)
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Cardano F., Del Canto E., Giordani S. Spiropyrans for light-controlled drug delivery // Dalton Transactions. 2019. Vol. 48. No. 41. pp. 15537-15544.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1039/c9dt02092f
UR - https://xlink.rsc.org/?DOI=C9DT02092F
TI - Spiropyrans for light-controlled drug delivery
T2 - Dalton Transactions
AU - Cardano, Francesca
AU - Del Canto, Elisa
AU - Giordani, Silvia
PY - 2019
DA - 2019/07/10
PB - Royal Society of Chemistry (RSC)
SP - 15537-15544
IS - 41
VL - 48
PMID - 31339137
SN - 1477-9226
SN - 1477-9234
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2019_Cardano,
author = {Francesca Cardano and Elisa Del Canto and Silvia Giordani},
title = {Spiropyrans for light-controlled drug delivery},
journal = {Dalton Transactions},
year = {2019},
volume = {48},
publisher = {Royal Society of Chemistry (RSC)},
month = {jul},
url = {https://xlink.rsc.org/?DOI=C9DT02092F},
number = {41},
pages = {15537--15544},
doi = {10.1039/c9dt02092f}
}
Cite this
MLA
Copy
Cardano, Francesca, et al. “Spiropyrans for light-controlled drug delivery.” Dalton Transactions, vol. 48, no. 41, Jul. 2019, pp. 15537-15544. https://xlink.rsc.org/?DOI=C9DT02092F.