Parahydrogen hyperpolarization of minimally altered urine samples for sensitivity enhanced NMR metabolomics
Publication type: Journal Article
Publication date: 2022-01-01
scimago Q1
wos Q2
SJR: 1.037
CiteScore: 7.4
Impact factor: 4.2
ISSN: 13597345, 1364548X
PubMed ID:
34908034
Materials Chemistry
Metals and Alloys
Surfaces, Coatings and Films
General Chemistry
Ceramics and Composites
Electronic, Optical and Magnetic Materials
Catalysis
Abstract
Parahydrogen hyperpolarization has been shown to enhance NMR sensitivity in urine analysis by several orders of magnitude if urine samples are prepared by solid phase extraction (SPE). We present a different approach, developed for minimal sample alteration before analysis. Removing SPE from the workflow allows to retain a wider range of metabolites and paves the way towards more universal hyperpolarized NMR metabolomics of low abundance metabolites.
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16
Total citations:
16
Citations from 2025:
3
(18.75%)
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GOST
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Ausmees K., Reimets N., Reile I. Parahydrogen hyperpolarization of minimally altered urine samples for sensitivity enhanced NMR metabolomics // Chemical Communications. 2022. Vol. 58. No. 3. pp. 463-466.
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Ausmees K., Reimets N., Reile I. Parahydrogen hyperpolarization of minimally altered urine samples for sensitivity enhanced NMR metabolomics // Chemical Communications. 2022. Vol. 58. No. 3. pp. 463-466.
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RIS
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TY - JOUR
DO - 10.1039/d1cc05665d
UR - https://xlink.rsc.org/?DOI=D1CC05665D
TI - Parahydrogen hyperpolarization of minimally altered urine samples for sensitivity enhanced NMR metabolomics
T2 - Chemical Communications
AU - Ausmees, Kerti
AU - Reimets, Nele
AU - Reile, Indrek
PY - 2022
DA - 2022/01/01
PB - Royal Society of Chemistry (RSC)
SP - 463-466
IS - 3
VL - 58
PMID - 34908034
SN - 1359-7345
SN - 1364-548X
ER -
Cite this
BibTex (up to 50 authors)
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@article{2022_Ausmees,
author = {Kerti Ausmees and Nele Reimets and Indrek Reile},
title = {Parahydrogen hyperpolarization of minimally altered urine samples for sensitivity enhanced NMR metabolomics},
journal = {Chemical Communications},
year = {2022},
volume = {58},
publisher = {Royal Society of Chemistry (RSC)},
month = {jan},
url = {https://xlink.rsc.org/?DOI=D1CC05665D},
number = {3},
pages = {463--466},
doi = {10.1039/d1cc05665d}
}
Cite this
MLA
Copy
Ausmees, Kerti, et al. “Parahydrogen hyperpolarization of minimally altered urine samples for sensitivity enhanced NMR metabolomics.” Chemical Communications, vol. 58, no. 3, Jan. 2022, pp. 463-466. https://xlink.rsc.org/?DOI=D1CC05665D.