Oxidative stress and reactive oxygen species: a review of their role in ocular disease
Тип публикации: Journal Article
Дата публикации: 2017-12-04
scimago Q1
wos Q1
БС1
SJR: 1.834
CiteScore: 10.9
Impact factor: 7.7
ISSN: 01435221, 14708736, 03010538, 01449664, 01444107, 00099287
PubMed ID:
29203723
General Medicine
Краткое описание
For many years, oxidative stress arising from the ubiquitous production of reactive oxygen species (ROS) has been implicated in the pathogenesis of various eye diseases. While emerging research has provided some evidence of the important physiological role of ROS in normal cell function, disease may arise where the concentration of ROS exceeds and overwhelms the body’s natural defence against them. Additionally, ROS may induce genomic aberrations which affect cellular homoeostasis and may result in disease. This literature review examines the current evidence for the role of oxidative stress in important ocular diseases with a view to identifying potential therapeutic targets for future study. The need is particularly pressing in developing treatments for conditions which remain notoriously difficult to treat, including glaucoma, diabetic retinopathy and age-related macular degeneration.
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Метрики
155
Всего цитирований:
155
Цитирований c 2025:
24
(15.49%)
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ГОСТ |
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BibTex |
MLA
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ГОСТ
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Ung L. et al. Oxidative stress and reactive oxygen species: a review of their role in ocular disease // Clinical Science. 2017. Vol. 131. No. 24. pp. 2865-2883.
ГОСТ со всеми авторами (до 50)
Скопировать
Ung L., Pattamatta U., Carnt N., Wilkinson-Berka J. L., Liew G., White A. J. Oxidative stress and reactive oxygen species: a review of their role in ocular disease // Clinical Science. 2017. Vol. 131. No. 24. pp. 2865-2883.
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RIS
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TY - JOUR
DO - 10.1042/cs20171246
UR - https://doi.org/10.1042/cs20171246
TI - Oxidative stress and reactive oxygen species: a review of their role in ocular disease
T2 - Clinical Science
AU - Ung, Lawson
AU - Pattamatta, Ushasree
AU - Carnt, Nicole
AU - Wilkinson-Berka, Jennifer L.
AU - Liew, Gerald
AU - White, Andrew J.R.
PY - 2017
DA - 2017/12/04
PB - Portland Press
SP - 2865-2883
IS - 24
VL - 131
PMID - 29203723
SN - 0143-5221
SN - 1470-8736
SN - 0301-0538
SN - 0144-9664
SN - 0144-4107
SN - 0009-9287
ER -
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BibTex (до 50 авторов)
Скопировать
@article{2017_Ung,
author = {Lawson Ung and Ushasree Pattamatta and Nicole Carnt and Jennifer L. Wilkinson-Berka and Gerald Liew and Andrew J.R. White},
title = {Oxidative stress and reactive oxygen species: a review of their role in ocular disease},
journal = {Clinical Science},
year = {2017},
volume = {131},
publisher = {Portland Press},
month = {dec},
url = {https://doi.org/10.1042/cs20171246},
number = {24},
pages = {2865--2883},
doi = {10.1042/cs20171246}
}
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MLA
Скопировать
Ung, Lawson, et al. “Oxidative stress and reactive oxygen species: a review of their role in ocular disease.” Clinical Science, vol. 131, no. 24, Dec. 2017, pp. 2865-2883. https://doi.org/10.1042/cs20171246.