Planta Medica, volume 58, issue 01, pages 56-59

Tyromycin A: a novel inhibitor of leucine and cysteine aminopeptidases from Tyromyces lacteus.

Publication typeJournal Article
Publication date1992-02-01
Journal: Planta Medica
scimago Q2
wos Q2
SJR0.445
CiteScore5.1
Impact factor2.1
ISSN00320943, 14390221
PubMed ID:  1620745
Organic Chemistry
Drug Discovery
Pharmacology
Pharmaceutical Science
Molecular Medicine
Complementary and alternative medicine
Analytical Chemistry
Abstract
Tyromycin A, a new inhibitor of leucine and cysteine aminopeptidases has been isolated from mycelial cultures of the basidiomycete Tyromyces lacteus (Fr.) Murr. Its structure was established as 1,16-bis-[4-methyl-2,5-dioxo-3-furyl]hexadecane (1) by spectral analysis and transformation into ester and imide derivatives.

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